Small molecule with a potentially big impact on Alzheimer's
date: 18/02/2016
Project: Stress cascades and Alzheimer's disease
acronym: STRESSAMYLOIDCASCADE
See also: CORDIS
Alzheimer’s current affects around 30 million people worldwide, and the figure is expected to rise as the population ages. The research, conducted in the EU-funded StressAmyloidCascade project, has demonstrated that drugs administered through the blood stream before the onset of Alzheimer-like symptoms in mice, can prevent age-associated cognitive impairments. The same treatment, based on a small-molecule synthetic compound called 7,8-DHF, also shows promise in slowing or even reversing cognitive decline after Alzheimer’s symptoms start to appear.