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MSCA fellow develops a pioneer procedure to test tumour treatments’ effectiveness

Scientists from the University of Cambridge, United Kingdom, have come up with a technique to establish early on if a cancer treatment is working. The results, published in Nature Medicine, confirm the method’s robustness. The lead author, Tiago Brandão Rodrigues, is a former Marie Skłodowska-Curie fellow.

It is known that the consumption of glucose (sugar) is much higher in tumours than in healthy tissues. Using this property of the tumour cells, Dr Rodrigues used a very sensitive modified magnetic resonance imaging (MRI) approach to produce images of the glucose consumption and metabolism of the tumour. The technique has been tested pre-clinically, and proved to be able to assess early response to cancer treatment. Clinical trials are at a preparatory stage. The lead author, Tiago Brandão Rodrigues, was supported by a 2-year Marie Skłodowska-Curie (MSCA) grant managed by the Research Executive Agency.

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