At 8 November 2022, a total of 12,103,931 COVID-19 cases and 256,066 deaths (CFR: 2.1%) have been reported by the 55 African Union (AU) Member States (MS). This represents 2% of all cases and 4% of all deaths reported globally. Since the detection of COVID-19 on the African continent (in February 2020), 53 (96%) AU MS have experienced three distinct COVID-19 waves, 48 (87%) MS have experienced four waves, 28 MS have experienced five waves, and five MS (Algeria, Burundi, Kenya, Mauritius and Tunisia) have experienced a sixth wave.