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European Partnership for Alternative Approaches to Animal Testing

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The European Partnership for Alternative Approaches to Animal Testing (EPAA) is an unprecedented voluntary collaboration between the European Commission, European trade associations, and companies from seven industry sectors.

The partners are committed to pooling knowledge and resources to accelerate the development, validation and acceptance of alternative approaches to animal use in regulatory testing. The overall aim is the replacement, reduction and refinement (3Rs) of animal use in regulatory testing.

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News and highlights

About the EPAA

History and rationale

Launched in November 2005 with the support of European Commissioner Verheugen and Potocnik, the EPAA began operations in 2006. It completed a first mandate of five years until end of 2010.

Due to the encouraging results of the projects undertaken by the EPAA, it has been decided to renew the mandate for another 5 year term. Priorities of this second mandate include Integrated Testing Strategies (lead theme 2011), International Collaboration on 3Rs (lead theme 2012-2013).

A more comprehensive Action Programme 2011-2015pdf (37 kB) is also available as well as the founding act of EPAA (3Rs Declaration)pdf (85 kB).


The vision of EPAA is the replacement, reduction and refinement (3Rs) of animal use for meeting regulatory requirements through better and more predictive science.

The EPAA Vision and Mission Paperpdf (340 kB)


Steering Committee

The EPAA Steering Committee, consisting of representatives of Partnership members, is responsible for providing strategic directions and for the adoption, implementation and review of the EPAA Action Programme 2011-2015pdf (37 kB). The Steering Committee meetings occur four times a year.

For transparency reasons, the Minutes of the EPAA Steering Committee meetings are public.

Mirror Group

The Mirror Group consists of representatives of so-called civil society and includes academia, animal welfare and patient groups. It acts as a consultation forum in an advisory capacity to the Steering Committee for the implementation of the Action Programme, as well as an institution from which the Steering Committee would seek comments on its activities from a broader societal perspective. The EPAA Mirror Group also meets quarterly.

For transparency reasons the Minutes of the EPAA Mirror Group meetings are public.

EPAA Secretariat

The EPAA is managed by a Secretariat to implement the decisions of the Steering Committee. This permanent team is hosted in Brussels, within the European Commission’s premises.

Enquiries should be sent to

Annual conferences

Annual reports