Since the EU Paediatric Regulation came into force ten years ago, 260 new medicines for children have been authorised. However, more effort is needed to combine the effects of the Paediatric with those of the "Orphan medicines" Regulation. EU Health Commissioner Vytenis Andriukaitis said: "When we consider the advances in adult oncology, it upsets me deeply that we have not made the same progress in treating the cancers that affect children. In the next 10 years we must focus on making similar breakthroughs for children, by combining the incentives under the Orphan and Paediatric Regulations, and by ensuring that the European Reference Networks - in particular on paediatric cancer, reach their full capacity".