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New Biocatalysis Data Have Been Reported by Researchers at Silesian University of Technology

Biotech News Daily | 30/10/2024 | Poland - Research findings on Biotechnology - Biocatalysis are discussed in a new report. According to news reporting out of Gliwice, Poland, by NewsRx editors, research stated, "This is a review on the feasibility of monolithic porous supports in biocatalysis carried out in a continuous flow system. It discusses factors affecting the efficiency and stability of enzyme immobilisation, kinetic parameters of enzyme processes carried out inside a monolith, biocatalysis in single and two-phase systems, and cascade reactions including cofactor regeneration." Funders for this research include European Union's European Innovation Council programme, Ministry of Education and Science (Poland) programme.

date:  30/10/2024

Our news journalists obtained a quote from the research from the Silesian University of Technology, "It also covers materials engineering (monolith types) and issues related to the flow of reactants through the monolith (chemical engineering). Emphasis is placed on the fact that the application of (bio)catalysis improves selectivity and atom economy, thus lowering the E factor. However, biocatalysts need to be employed in a reactor, which can aid further improvement towards green chemistry goals. The application of enzymes in flow chemistry has been shown to lead to higher space time yields (STYs) compared to batch reactions. In particular, with monolithic reactors a drastic decrease in volume and thus solvent can be achieved.

By immobilising very high densities of enzymes directly on the monolith, reaction times dwindle, improving STYs. The small reaction volumes enable excellent heat transfer, helping to save energy. The underlying principles of monolithic flow reactors and their application in mono- and bi-phasic biocatalytic systems will be examined. Biocatalysis in flow improves space time yields and enables straightforward downstream processing."

According to the news editors, the research concluded: "The underlying principles of monolithic flow reactors and their application in mono- and bi-phasic biocatalytic systems are discussed."

This research has been peer-reviewed.

For more information on this research see: Monoliths Enabling Biocatalysis In Flow Chemistry. Green Chemistry, 2024. Green Chemistry can be contacted at: Royal Soc Chemistry, Thomas Graham House, Science Park, Milton Rd, Cambridge CB4 0WF, Cambs, England. (Royal Society of Chemistry - www.rsc.org/; Green Chemistry - pubs.rsc.org/en/journals/journalissues/gc)

Our news journalists report that additional information may be obtained by contacting Katarzyna Szymanska, Silesian University of Technology, Dept. of Chemical Engineering and Process Design, Ks M Strzody 7, Pl-44100 Gliwice, Poland. Additional authors for this research include Aleksandra Lambarska and Ulf Hanefeld.