This study's purpose is to provide a scientific assessment of the state of cross-border cooperation between European states in the geographical area of Balkan and Danube European countries. It applies the so-called SWOT methodology to assess the extent and depth of cross-border cooperation thus giving both a quantitative and qualitative appraisal. This is followed by the identification of the most appropriate “strategy” recommended in order to achieve the best possible cross-border cooperation (removing obstacles, skipping threats, exploiting opportunities, healing weaknesses).