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Directorate-General for Health and Food Safety
1. Welcoming address, apologies for
absence and declarations of interest
Due to the late arrival of the Chairman of the CSTEE, it was the first Vice Chairman who opened the session and chaired it during first 30 minutes (while discussing points 1 to 3 of the Agenda).
Professor Peter Calow, new member of the CSTEE was introduced to the Committee.
Apologies were received from Prof. Wennig.
Dr Tarazona expressed a declaration of interest on the point of Cumene (substance evaluated under the Existing Substances Regulation 793/93/EC). He explained that he participated in the preparation of the Risk Assessment Report on behalf of the Spanish authorities (Spain was the rapporteur Member State for this substance) and took no further part in the discussion.
2. Adoption of the draft agenda
The draft agenda was adopted, with the agreement of the CSTEE that point 8 would be the first one to be discussed in the afternoon.
3. Adoption of the draft minutes of the 12th and 13th CSTEE plenary meetings held respectively on the 25th of November 1999 and on the 4th of February 2000 in Brussels
The minutes of the 12th and 13th plenary meetings of the CSTEE were adopted.
4. Change in the schedule of CSTEE plenary meetings for the year 2000
Due to the impossibility for adopting some important opinions during the meeting, an additional extraordinary one was decided for 5 May 2000.
The plenary meeting of November 2000 was rescheduled for the 8-9 November 2000 with the 8 as the preferred date in case of a one-day meeting. The preferred dates for the June and September plenary meetings were changed to be 20 June and 5 September respectively.
5. Presentation by representatives of the Rijkinstituut voor Volksgezondheid en Milieu (RIVM), Nederland, of their ongoing research project relating to the development and validation of a test method for the identification of endocrine disrupting chemicals
Representatives from RIVM made a presentation which was followed by a detailed discussion. An important element of the RIVM project was agreed by members to be the fish atlas, designed to offer material for the normal histology and toxicological pathology with emphasis on effects of endocrine disruption. It expected to find application in the screening for ecotoxicity. One CSTEE member expressed some concern about the importance given to histology in the study with insufficient evidence given to the relation between histological change and reproductive effects;. A question was also raised about the possibility of testing the relation between laboratory and ecosystem behaviour by choosing a species which could be examined in both situations. Committee members were assured that the atlas will be developed further as and when new data becomes available. The project is on course to deliver on time (in which the OECD seems to be very interested).
6. Lead - Danish notification 595/98/DK - for opinion
The draft was extensively discussed. Many CSTEE members commented on different points of the draft opinion. Because of the nature of some of these comments (which strictly could not be considered only editorial) it was decided that the CSTEE members with reservations should send them to the WG chairman, to the editor of the opinion, and to the CSTEE secretariat. Under these circumstances the opinion could not, at that stage, be considered finally adopted. Since an extraordinary plenary meeting was already scheduled for 5 May this was considered a good opportunity to sort out the few areas of concern and to adopt the opinion then.
7. Regulation 793/93 on Existing substances (ESR):
Prior to the discussion on the actual drafts, the CSTEE chairman initiated a discussion on where it was felt that the CSTEE could best contribute to the proposed general strategy to deal with each report, and the necessity of harmonising the style of presentation of the opinions.
The CSTEE Secretary informed the Committee about a meeting, held the week before the plenary, between Health and Consumer Protection DG and Environment DG to discuss the possibility of submitting to the CSTEE the so called "informal consultations" on the reports while they are still under discussion in the technical meetings in the JRC-ECB, prior, therefore, to their final stage. He explained the advantages and problems of this approach and some CSTEE members expressed their views on this.
A representative from Environment DG gave a general view of what would be the follow up of the opinions expressed by CSTEE. They would be submitted to the JRC to be considered for revision of the Risk Assessment Reports in the Technical Meetings. They would be considered, as well, in any Risk Reduction Strategy to be adopted in the future. Finally he asked the Committee for any comments on methodology, in the framework of the previous mentioned informal consultation, and to point out any particular question that should be taken into account by Commission Services.
Some CSTEE members asked about the acknowledgement given to the advice provided by the Committee, whether it was accepted by the Commission Services involved or not. From their point of view that would show clearly the transparency and independence of the Committees.
A. Progress reports/opinions on:
- Hydrogen Fluoride
- Dimethyl sulphate
- 4'4-Methylenedianiline
- Cumene
- Acrolein
The drafts were presented and discussed. As was the case with point 6 of the Agenda, here too, reservations of various sorts prevented the CSTEE from the final adoption of these opinions. The adoptions were postponed until the extraordinary Plenary Meeting of 5 May.
The question was raised on the acceptability or not of the use of certain uncertainty factors in the Margins of Safety (MOS) to compensate gaps in the database. Some of the CSTEE members expressed their concern about that, especially due to the danger of accepting that as a consequence there will be no necessity to fill in these gaps. A representative of JRC-ECB explained that the same concerns were already expressed in their technical meetings, and asked the Committee for suggestions on possible alternatives to the use of these uncertainty factors.
Regarding the report on Hydrogen Fluoride, one CSTEE member considered that the question of marine effects was not adequately addressed in the report. He was invited to draft a text on that, in the context that this is a general issue affecting many chemicals and not only this particular one.
During the discussion of the report on Dimethyl sulphate a concern was expressed among CSTEE members on the meaning of the term "worst case scenario", used sometimes even when there are not enough data to define it. A further written explanation on this important issue was deemed necessary.
B. State of play regarding the consultation of the CSTEE on other substances evaluated under the ESR:
Consultation of the CSTEE on the human health effects report of:
- Pentabromodiphenyl ether.
DG Environment confirmed that they can wait till the June plenary for the adoption of the human effects part of this Report (the CSTEE had already adopted the opinion on the environmental part).
Consultation of the CSTEE on the environmental effects report of:
- Octabromodiphenyl ether
- Decabromodiphenyl ether
These two were also not considered urgent by Environment DG (the Commission service responsible for them), and they were postponed for adoption to the June meeting,.
8. Consultation of the CSTEE on the following reports on Methylene chloride and certain Chemicals in Textiles" submitted by DG Enterprise:
A - "Methylene chloride: Advantages and Drawbacks of Possible Market Restrictions in the EU" - TNO (Dr. Tukker & Ir. L.Ph. Simons - NL) report STB-99-53 Final - November 1999 (CSTEE/2000/5 - Add. 1).
B - "Assessment of the Risks to Human Health Posed by Certain Chemicals in Textiles and of the Advantages and Drawbacks of Restrictions on their Marketing and Use" - Final Report - July 1999 - WS Atkins International Ltd (UK) - (CSTEE/2000/5 - Add. 2).
A draft opinion was presented. The rapporteur explained that one of the major problems found in the report was that the chemicals were referred to only by the name of the Colour Index, not by the formula or Chemical Abstract Service number (CAS Number). The report limits its references to two aspects: sensitisation and carcinogenicity. Some weaknesses of the report were pointed out on both aspects. Regarding the occupational and consumer exposure, the document only deals with dermal exposure. From the point of view of the rapporteur at least oral exposure should have been considered for consumers, because of the possibility of children being exposed to very high doses of dyes through chewing and sucking textiles. It was also pointed out that there was a lack of toxicity information for many of the dyes.
A representative from Enterprise DG was requested to explain the background of the reports both on dyes and on Methylene chloride.
It was considered very important to identify the structure of each of the chemicals under consideration (azo dyes and anthraquinone dyes), in order to look at their structure activity relationship. Therefore, before the opinion could be considered ready for adoption at least a meeting of the working party was deemed necessary. Enterprise DG, the responsible service for that dossier, accepted the delay in adoption to probably the June Plenary meeting.
9. Scientific experts in Toxicology, Ecotoxicology and Epidemiology for risk assessments - planning for the future
Prof. Bridges presented a draft document prepared by him and Profs. Greim and Dybing. Attention is drawn in this document to the gradually loss of high level expertise in those disciplines in Europe. The proposal was agreed that CSTEE, as the Scientific Committee with the greatest involvement in each of these areas would develop the document as an Opinion to be submitted to the Commission. A working group was set up to further refine the draft.
10. The use of measured exposure data in risk assessments - progress report
No time was available to discuss this in depth. The chairman of the working group had prepared a draft table of contents for the report to be adopted by the CSTEE. A meeting of the working group would take place soon.
11. Available scientific approaches to assess the potential effects and risks of chemical substances on terrestrial ecosystems - progress report
A new draft text was available but a new working group meeting was expected to take place on 8 May for making progress.
12. Strategies for dealing with possible additional opinion requests submitted by other DGs of the Commission
a) "Programme of procedures for the assessment of risks to health and the environment from cadmium in fertilisers"
The setting up of a WG was decided to tackle this opinion request. A WG meeting was deemed necessary and, therefore, would be soon organised.
b) Other
The CSTEE secretariat informed the committee about the upcoming consultation on Endocrine Disrupting Chemicals (priority list of substances that are suspected of having ED properties). The submission would take place in June and the opinion would be necessary for the October 2000 plenary at the latest.
13. Feedback from the relevant services of the Commission on the follow up to the opinions adopted previously by the CSTEE
The CSTEE secretary informed the committee about a meeting that took place the week before in Ispra on the development/validation of a test method for determining phthalate migration. The meeting was a difficult one in the sense that participants agreed that the technical difficulties of such an exercise are significant. The ECB will produce a report soon. In principle the CSTEE will be asked an opinion on some methodological aspects on which clarification is still needed before the further development of the method itself is pursued.
14. Update by the CSTEE chairman on the latest meetings of the Scientific Steering Committee on matters of interest to the CSTEE
No feed back was possible on this for lack of time.
15. Arrangements for the next meeting of the CSTEE
The decision was taken to have an extraordinary meeting on 5 May 2000, essentially to solve the problem of the outstanding adoption of the opinions on substances under the Existing Substances Regulation 793/93/EC, but other outstanding agenda items could be sorted out as well during that meeting.
16. Any other business
The chairman of the working group on phthalates presented his conclusions on very recent data on the change in the classification of DEHP for carcinogenic effects. A possible future change in the MOS (Margin Of Safety) of 100 for DEHP (may have to take place because once data is available it no longer makes sense to establish arbitrary uncertainty factors such as the one of 100 chosen for DEHP); this may lead to a change in the level of concern for this chemical.
- AGENDA -
1. Welcoming address, apologies for absence and declarations of interest
2. Adoption of the draft agenda
3. Adoption of the draft minutes of the 12th and 13th CSTEE plenary meetings held respectively on the 25th of November 1999 and on the 4th of February 2000 in Brussels
4. Change in the schedule of CSTEE plenary meetings for the year 2000
5. Presentation by representatives of the Rijkinstituut voor Volksgezondheid en Milieu (RIVM), Nederland, of their ongoing research project relating to the development and validation of a test method for the identification of endocrine disrupting chemicals
6. Lead - Danish notification 595/98/DK - for opinion
7. Regulation 793/93 on Existing substances (ESR):
A. Progress reports/opinions on:
- Hydrogen Fluoride
- Dimethyl sulphate
- 4'4-Methylenedianiline
- Cumene
- Acrolein
B. State of play regarding the consultation of the CSTEE on other substances evaluated under the ESR:
Consultation of the CSTEE on the human health effects report of:
- Pentabromodiphenyl ether.
Consultation of the CSTEE on the environmental effects report of:
- Octabromodiphenyl ether
- Decabromodiphenyl ether
8. Consultation of the CSTEE on the following reports on Methylene chloride and certain Chemicals in Textiles" submitted by DG Enterprise:
A - "Methylene chloride: Advantages and Drawbacks of Possible Market Restrictions in the EU" - TNO (Dr. Tukker & Ir. L.Ph. Simons - NL) report STB-99-53 Final - November 1999 (CSTEE/2000/5 - Add. 1).
B - "Assessment of the Risks to Human Health Posed by Certain Chemicals in Textiles and of the Advantages and Drawbacks of Restrictions on their Marketing and Use" - Final Report - July 1999 - WS Atkins International Ltd (UK) - (CSTEE/2000/5 - Add. 2).
9. The use of measured exposure data in risk assessments - progress report
10. Available scientific approaches to assess the potential effects and risks of chemical substances on terrestrial ecosystems - progress report
11. Strategies for dealing with possible additional opinion requests submitted by other DGs of the Commission
12. Feedback from the relevant services of the Commission on the follow up to the opinions adopted previously by the CSTEE
13. Update by the CSTEE chairman on the latest meetings of the Scientific Steering Committee on matters of interest to the CSTEE
14. Arrangements for the next meeting of the CSTEE
15. Any other business
LIST OF PARTICIPANTS
CSTEE:
Prof. James W. BRIDGES, Prof. Peter Calow, Dr. Mark J. COSTELLO, Prof. Erik DYBING, Prof. Helmut A. GREIM, Prof. Bo O. JANSSON, Prof. Soterios A. KYRTOPOULOS, Prof. Ole LADEFOGED, Dr. Claude Lambré, Prof. Dr. José RUEFF, Prof. Mirja S. SALKINOJA-SALONEN, Dr. José V. TARAZONA, Prof. Benedetto TERRACINI, Prof. Janneche UTNE-SKÅRE, Prof. Katarina VICTORIN, Prof. Marco VIGHI.
Ad-Hoc Experts:
Dr. Peter WESTER, Dr. van de VEN.
European Commission:
HEALTH AND CONSUMER PROTECTION DG:
Mr. Jorge COSTA-DAVID, Mr. Juan B. CRESPO ARCE, Mr. Panagiotis DASKALEROS, Mrs. Mercedes de SOLÀ.
ENTERPRISE DG:
Mr. Joachim EHRENBERG, Mr. Vincenzo GENTE, Mrs. Lena PERENIUS.
ENVIRONMENT DG:
Mr. Peter DREW, Mr. Paul HAYES, Mr. Alexandre PAQUOT, Mrs. Birgit van TONGELEN.
RESEARCH DG:
Mrs. Kirsi HAAVISTO.
JOINT RESEARCH CENTRE:
Mrs. Sharon MUNN
Due to the late arrival of the Chairman of the CSTEE, it was the first Vice Chairman who opened the session and chaired it during first 30 minutes (while discussing points 1 to 3 of the Agenda).
Professor Peter Calow, new member of the CSTEE was introduced to the Committee.
Apologies were received from Prof. Wennig.
Dr Tarazona expressed a declaration of interest on the point of Cumene (substance evaluated under the Existing Substances Regulation 793/93/EC). He explained that he participated in the preparation of the Risk Assessment Report on behalf of the Spanish authorities (Spain was the rapporteur Member State for this substance) and took no further part in the discussion.
2. Adoption of the draft agenda
The draft agenda was adopted, with the agreement of the CSTEE that point 8 would be the first one to be discussed in the afternoon.
3. Adoption of the draft minutes of the 12th and 13th CSTEE plenary meetings held respectively on the 25th of November 1999 and on the 4th of February 2000 in Brussels
The minutes of the 12th and 13th plenary meetings of the CSTEE were adopted.
4. Change in the schedule of CSTEE plenary meetings for the year 2000
Due to the impossibility for adopting some important opinions during the meeting, an additional extraordinary one was decided for 5 May 2000.
The plenary meeting of November 2000 was rescheduled for the 8-9 November 2000 with the 8 as the preferred date in case of a one-day meeting. The preferred dates for the June and September plenary meetings were changed to be 20 June and 5 September respectively.
5. Presentation by representatives of the Rijkinstituut voor Volksgezondheid en Milieu (RIVM), Nederland, of their ongoing research project relating to the development and validation of a test method for the identification of endocrine disrupting chemicals
Representatives from RIVM made a presentation which was followed by a detailed discussion. An important element of the RIVM project was agreed by members to be the fish atlas, designed to offer material for the normal histology and toxicological pathology with emphasis on effects of endocrine disruption. It expected to find application in the screening for ecotoxicity. One CSTEE member expressed some concern about the importance given to histology in the study with insufficient evidence given to the relation between histological change and reproductive effects;. A question was also raised about the possibility of testing the relation between laboratory and ecosystem behaviour by choosing a species which could be examined in both situations. Committee members were assured that the atlas will be developed further as and when new data becomes available. The project is on course to deliver on time (in which the OECD seems to be very interested).
6. Lead - Danish notification 595/98/DK - for opinion
The draft was extensively discussed. Many CSTEE members commented on different points of the draft opinion. Because of the nature of some of these comments (which strictly could not be considered only editorial) it was decided that the CSTEE members with reservations should send them to the WG chairman, to the editor of the opinion, and to the CSTEE secretariat. Under these circumstances the opinion could not, at that stage, be considered finally adopted. Since an extraordinary plenary meeting was already scheduled for 5 May this was considered a good opportunity to sort out the few areas of concern and to adopt the opinion then.
7. Regulation 793/93 on Existing substances (ESR):
Prior to the discussion on the actual drafts, the CSTEE chairman initiated a discussion on where it was felt that the CSTEE could best contribute to the proposed general strategy to deal with each report, and the necessity of harmonising the style of presentation of the opinions.
The CSTEE Secretary informed the Committee about a meeting, held the week before the plenary, between Health and Consumer Protection DG and Environment DG to discuss the possibility of submitting to the CSTEE the so called "informal consultations" on the reports while they are still under discussion in the technical meetings in the JRC-ECB, prior, therefore, to their final stage. He explained the advantages and problems of this approach and some CSTEE members expressed their views on this.
A representative from Environment DG gave a general view of what would be the follow up of the opinions expressed by CSTEE. They would be submitted to the JRC to be considered for revision of the Risk Assessment Reports in the Technical Meetings. They would be considered, as well, in any Risk Reduction Strategy to be adopted in the future. Finally he asked the Committee for any comments on methodology, in the framework of the previous mentioned informal consultation, and to point out any particular question that should be taken into account by Commission Services.
Some CSTEE members asked about the acknowledgement given to the advice provided by the Committee, whether it was accepted by the Commission Services involved or not. From their point of view that would show clearly the transparency and independence of the Committees.
A. Progress reports/opinions on:
- Hydrogen Fluoride
- Dimethyl sulphate
- 4'4-Methylenedianiline
- Cumene
- Acrolein
The drafts were presented and discussed. As was the case with point 6 of the Agenda, here too, reservations of various sorts prevented the CSTEE from the final adoption of these opinions. The adoptions were postponed until the extraordinary Plenary Meeting of 5 May.
The question was raised on the acceptability or not of the use of certain uncertainty factors in the Margins of Safety (MOS) to compensate gaps in the database. Some of the CSTEE members expressed their concern about that, especially due to the danger of accepting that as a consequence there will be no necessity to fill in these gaps. A representative of JRC-ECB explained that the same concerns were already expressed in their technical meetings, and asked the Committee for suggestions on possible alternatives to the use of these uncertainty factors.
Regarding the report on Hydrogen Fluoride, one CSTEE member considered that the question of marine effects was not adequately addressed in the report. He was invited to draft a text on that, in the context that this is a general issue affecting many chemicals and not only this particular one.
During the discussion of the report on Dimethyl sulphate a concern was expressed among CSTEE members on the meaning of the term "worst case scenario", used sometimes even when there are not enough data to define it. A further written explanation on this important issue was deemed necessary.
B. State of play regarding the consultation of the CSTEE on other substances evaluated under the ESR:
Consultation of the CSTEE on the human health effects report of:
- Pentabromodiphenyl ether.
DG Environment confirmed that they can wait till the June plenary for the adoption of the human effects part of this Report (the CSTEE had already adopted the opinion on the environmental part).
Consultation of the CSTEE on the environmental effects report of:
- Octabromodiphenyl ether
- Decabromodiphenyl ether
These two were also not considered urgent by Environment DG (the Commission service responsible for them), and they were postponed for adoption to the June meeting,.
8. Consultation of the CSTEE on the following reports on Methylene chloride and certain Chemicals in Textiles" submitted by DG Enterprise:
A - "Methylene chloride: Advantages and Drawbacks of Possible Market Restrictions in the EU" - TNO (Dr. Tukker & Ir. L.Ph. Simons - NL) report STB-99-53 Final - November 1999 (CSTEE/2000/5 - Add. 1).
B - "Assessment of the Risks to Human Health Posed by Certain Chemicals in Textiles and of the Advantages and Drawbacks of Restrictions on their Marketing and Use" - Final Report - July 1999 - WS Atkins International Ltd (UK) - (CSTEE/2000/5 - Add. 2).
A draft opinion was presented. The rapporteur explained that one of the major problems found in the report was that the chemicals were referred to only by the name of the Colour Index, not by the formula or Chemical Abstract Service number (CAS Number). The report limits its references to two aspects: sensitisation and carcinogenicity. Some weaknesses of the report were pointed out on both aspects. Regarding the occupational and consumer exposure, the document only deals with dermal exposure. From the point of view of the rapporteur at least oral exposure should have been considered for consumers, because of the possibility of children being exposed to very high doses of dyes through chewing and sucking textiles. It was also pointed out that there was a lack of toxicity information for many of the dyes.
A representative from Enterprise DG was requested to explain the background of the reports both on dyes and on Methylene chloride.
It was considered very important to identify the structure of each of the chemicals under consideration (azo dyes and anthraquinone dyes), in order to look at their structure activity relationship. Therefore, before the opinion could be considered ready for adoption at least a meeting of the working party was deemed necessary. Enterprise DG, the responsible service for that dossier, accepted the delay in adoption to probably the June Plenary meeting.
9. Scientific experts in Toxicology, Ecotoxicology and Epidemiology for risk assessments - planning for the future
Prof. Bridges presented a draft document prepared by him and Profs. Greim and Dybing. Attention is drawn in this document to the gradually loss of high level expertise in those disciplines in Europe. The proposal was agreed that CSTEE, as the Scientific Committee with the greatest involvement in each of these areas would develop the document as an Opinion to be submitted to the Commission. A working group was set up to further refine the draft.
10. The use of measured exposure data in risk assessments - progress report
No time was available to discuss this in depth. The chairman of the working group had prepared a draft table of contents for the report to be adopted by the CSTEE. A meeting of the working group would take place soon.
11. Available scientific approaches to assess the potential effects and risks of chemical substances on terrestrial ecosystems - progress report
A new draft text was available but a new working group meeting was expected to take place on 8 May for making progress.
12. Strategies for dealing with possible additional opinion requests submitted by other DGs of the Commission
a) "Programme of procedures for the assessment of risks to health and the environment from cadmium in fertilisers"
The setting up of a WG was decided to tackle this opinion request. A WG meeting was deemed necessary and, therefore, would be soon organised.
b) Other
The CSTEE secretariat informed the committee about the upcoming consultation on Endocrine Disrupting Chemicals (priority list of substances that are suspected of having ED properties). The submission would take place in June and the opinion would be necessary for the October 2000 plenary at the latest.
13. Feedback from the relevant services of the Commission on the follow up to the opinions adopted previously by the CSTEE
The CSTEE secretary informed the committee about a meeting that took place the week before in Ispra on the development/validation of a test method for determining phthalate migration. The meeting was a difficult one in the sense that participants agreed that the technical difficulties of such an exercise are significant. The ECB will produce a report soon. In principle the CSTEE will be asked an opinion on some methodological aspects on which clarification is still needed before the further development of the method itself is pursued.
14. Update by the CSTEE chairman on the latest meetings of the Scientific Steering Committee on matters of interest to the CSTEE
No feed back was possible on this for lack of time.
15. Arrangements for the next meeting of the CSTEE
The decision was taken to have an extraordinary meeting on 5 May 2000, essentially to solve the problem of the outstanding adoption of the opinions on substances under the Existing Substances Regulation 793/93/EC, but other outstanding agenda items could be sorted out as well during that meeting.
16. Any other business
The chairman of the working group on phthalates presented his conclusions on very recent data on the change in the classification of DEHP for carcinogenic effects. A possible future change in the MOS (Margin Of Safety) of 100 for DEHP (may have to take place because once data is available it no longer makes sense to establish arbitrary uncertainty factors such as the one of 100 chosen for DEHP); this may lead to a change in the level of concern for this chemical.
- AGENDA -
1. Welcoming address, apologies for absence and declarations of interest
2. Adoption of the draft agenda
3. Adoption of the draft minutes of the 12th and 13th CSTEE plenary meetings held respectively on the 25th of November 1999 and on the 4th of February 2000 in Brussels
4. Change in the schedule of CSTEE plenary meetings for the year 2000
5. Presentation by representatives of the Rijkinstituut voor Volksgezondheid en Milieu (RIVM), Nederland, of their ongoing research project relating to the development and validation of a test method for the identification of endocrine disrupting chemicals
6. Lead - Danish notification 595/98/DK - for opinion
7. Regulation 793/93 on Existing substances (ESR):
A. Progress reports/opinions on:
- Hydrogen Fluoride
- Dimethyl sulphate
- 4'4-Methylenedianiline
- Cumene
- Acrolein
B. State of play regarding the consultation of the CSTEE on other substances evaluated under the ESR:
Consultation of the CSTEE on the human health effects report of:
- Pentabromodiphenyl ether.
Consultation of the CSTEE on the environmental effects report of:
- Octabromodiphenyl ether
- Decabromodiphenyl ether
8. Consultation of the CSTEE on the following reports on Methylene chloride and certain Chemicals in Textiles" submitted by DG Enterprise:
A - "Methylene chloride: Advantages and Drawbacks of Possible Market Restrictions in the EU" - TNO (Dr. Tukker & Ir. L.Ph. Simons - NL) report STB-99-53 Final - November 1999 (CSTEE/2000/5 - Add. 1).
B - "Assessment of the Risks to Human Health Posed by Certain Chemicals in Textiles and of the Advantages and Drawbacks of Restrictions on their Marketing and Use" - Final Report - July 1999 - WS Atkins International Ltd (UK) - (CSTEE/2000/5 - Add. 2).
9. The use of measured exposure data in risk assessments - progress report
10. Available scientific approaches to assess the potential effects and risks of chemical substances on terrestrial ecosystems - progress report
11. Strategies for dealing with possible additional opinion requests submitted by other DGs of the Commission
12. Feedback from the relevant services of the Commission on the follow up to the opinions adopted previously by the CSTEE
13. Update by the CSTEE chairman on the latest meetings of the Scientific Steering Committee on matters of interest to the CSTEE
14. Arrangements for the next meeting of the CSTEE
15. Any other business
LIST OF PARTICIPANTS
CSTEE:
Prof. James W. BRIDGES, Prof. Peter Calow, Dr. Mark J. COSTELLO, Prof. Erik DYBING, Prof. Helmut A. GREIM, Prof. Bo O. JANSSON, Prof. Soterios A. KYRTOPOULOS, Prof. Ole LADEFOGED, Dr. Claude Lambré, Prof. Dr. José RUEFF, Prof. Mirja S. SALKINOJA-SALONEN, Dr. José V. TARAZONA, Prof. Benedetto TERRACINI, Prof. Janneche UTNE-SKÅRE, Prof. Katarina VICTORIN, Prof. Marco VIGHI.
Ad-Hoc Experts:
Dr. Peter WESTER, Dr. van de VEN.
European Commission:
HEALTH AND CONSUMER PROTECTION DG:
Mr. Jorge COSTA-DAVID, Mr. Juan B. CRESPO ARCE, Mr. Panagiotis DASKALEROS, Mrs. Mercedes de SOLÀ.
ENTERPRISE DG:
Mr. Joachim EHRENBERG, Mr. Vincenzo GENTE, Mrs. Lena PERENIUS.
ENVIRONMENT DG:
Mr. Peter DREW, Mr. Paul HAYES, Mr. Alexandre PAQUOT, Mrs. Birgit van TONGELEN.
RESEARCH DG:
Mrs. Kirsi HAAVISTO.
JOINT RESEARCH CENTRE:
Mrs. Sharon MUNN
