ICH E6 R3 principles and Annex 1 published
date: 21/03/2025
The ICH E6(R3) principles and Annex 1 have been published. The update aims to adapt good clinical practice principles to recent developments in trial design, increasingly diverse trial types and data sources that support decision-making on medicines. The revised guideline also provides flexibilities to facilitate the use of technological innovations in clinical trials (see also related workshop).