Health
Scientific Committees
Scientific Steering Committee (former MDSC)
Outcome of discussions
The safe
handling, transport and temporary storage of meat-and-bone
meal which may be contaminated with a BSE agent or other
pathogens - Notes adopted by the Scientific Steering
Committee at its meeting of 26-27 October 2000
Table of Contents
Preliminary Note
Background
a. Well contained mbm storage
conditions
b. Standard of cleanliness
c. Effective measures for the protection
of workers
d. Safe transport
Acknowledgements
References
Preliminary Note
The issue of handing, transport and
storage of possibly BSE-contaminated meat-and-bone meal
(MBM) as a hazard has been highlighted in various SSC
opinions. The present document consists of a series of
notes that may be helpful for decision makers when
developing measures to contain this hazard. These measures
may possibly need to be modulated according to the
geographical BSE risk of a region or country.
The document is not meant to be
comprehensive and is subject to amendments should relevant
information become available.
It was first compiled for the Scientific
Steering Committee at its meeting of 25-26 May 2000. This
was made public via internet as a set of preliminary and
incomplete notes, for comments and additional scientific
inputs.
Written contributions were received
from:
- Prof.Dr.H.Budka, University of Vienna
- Austria.
- Mr. Toby Cotton, Durga Environmental
Ltd, Derbyshire - United Kingdom
- Mr R.Gellez, Association Le Gallet
Environnement, Le Gallet - France
- Dr.Henrik Holst-Pedersen, Kambas,
Ringsted - Denmark
- Mme A.Leroy, Coordination des
Associations de Riverains d'Usines d'Équarrissage, Le Havre
- France
- Mr.R.Medrano, Italy
- Mr.R.Moya, Association pour la
Protection et la Défense de la Qualité de l'Atmosphère de
la Commune de Virat et des Environs, Bourg en Bresse -
France
- Mr. Ernest Peillon, Association de
Défense des Sites Crêt Fonds Perdu, Reveux et Méons,
Saint-Jean Bonnefonds - France
- Prof. Dr.G. Piva, Catholic University
of Sacred Heart, Piacenza - Italy
- Dr.D.Taylor, SEDACON Consultancy
Bureau Edinburg - United Kingdom)
- Dr.John Wilesmith - Ministry of
Agriculture, Fisheries and Food - United Kingdom
- Prof.Dr.R.G.Will, Edinburgh - United
Kingdom
The Scientific Steering Committee
analysed, discussed and, if found appropriate, integrated
these contributions in the present significantly revised
report, which was submitted to the SSC at its meeting 26-27
October 2000.
_______________
Background
In its previous opinions, the SSC has
addressed the problem of excluding specific risk materials
from entering the food chain directly and the safe disposal
of possibly contaminated material. The SSC has not
previously addressed the question of the safe handling
,
storage and transport of possible BSE or other
pathogen contaminated material that is destined for
disposal. These Notes are centred on issues relating to BSE
however it is relevant to the storage and handling of many
other TSEs and other pathogen contaminated materials
too.
Safe storage of pathogenic or
potentially pathogenic material is an essential element in
the protection of animal andhuman health, and of the
environment. It can become of major importance if a large
number of animals are required to be slaughtered over a
short period of time in order to control an epidemic, and
there is inadequate capacity for immediate safe processing
and/or disposal. Storage may involve intact or dismembered
carcasses and/or processed materials such as MBM derived
from suspect carcasses.
Production of MBM by rendering in steam
for 20 minutes at 133
oc at a pressure of 3 bars has been identified
as a very important step in reducing the risk substantially
from BSE contaminated material. However, because MBM
produced in the UK is no longer fed to any species of
farmed animal, the UK renderers have opted not to change to
the steam-under-pressure system, and continue to use the
more traditional but less inactivating rendering
processes.
Depending on the capacity of a
countries' rendering plants to manage the sudden increase
in demand, an accumulation of animal tissues and/or of
rendered material may occur prior to disposal by approved
safe routes. In the case of BSE, the great majority of
stored material for disposal comprises meat and bone meal
and to a much lesser extent, tallow. It has been the case
in some countries that the quantity of material requiring
safe disposal, as a consequence of the BSE epidemic, has
overwhelmed the storage capacity set aside to deal with
potentially pathogenic/toxic material. This has identified
the need for guidelines of what should be the minimum
criteria for safe storage and safe disposal in an emergency
situation in order to protect the workforce (ie: those
involved in handling the potentially contaminated
material), the general public and the environment. It also
raises the important issue of the adequacy of the capacity
for safe storage and disposal facilities in emergency
situations in member states.
The more specific the criteria are for
disposal the greater is likely to be the requirement for
storage capacity. Some countries, such as Switzerland, have
elected to combust all additional potentially suspect
material in power stations and have consequently minimised
the requirements for storage capacity. However, the SSC has
not recommended this method of disposal to Member States to
date because of the lack of evidence available to the
Committee to demonstrate its suitability in terms of
safety. Other countries, for example the UK, have been much
more restrictive in the approval of disposal methods and as
a consequence have had to find suitable storage capacity
for large quantities of meat and bone meal and
tallow.
The purpose of this opinion is to
provide some advise on the safe storage and transport of
meat and bone meal and of carcasses prior to, and post
rendering. It does not address, however, the risk to
abattoir workers involved in stunning, killing, collecting
blood and carcass preparation from food animals.
There have been several highly
publicised incidents in which stored MBM material has
either caught fire or has been shown to have not been
contained effectively within the designated storage area.
There is also evidence of poor storage conditions resulting
in MBM setting like concrete, resulting in subsequent
difficulties in disposal.
There are four important requisites to
minimise the risk associated with storage of possible
BSE-contaminated materials:
A. well contained storage
conditions;
B. high standards of cleanliness
C. good worker protection
D. safe transport.
The SSC notes that these requirements
are similar to those for minimising the risk for many other
hazardous materials and that some Member States have
already developed their own guidelines for dealing with
possibly TSE-contaminated materials.
a. Well contained mbm storage conditions
For worker protection, the principal
requirements are to minimise dermal contact with the MBM
and keep dust levels very low to avoid contact with the
eyes and respiratory system. When first produced MBM does
not readily produce dust because of its relatively high fat
content
.
However, after long-term storage it may set in large
blocks which require to be broken up. This procedure has
the potential to produced airborne particulate
matter.
The requirement in terms of protection
of the public and the environment should be considered in
the light of the magnitude of the potential risks from poor
control over access to or containment of potentially
contaminated MBM. The following aspects need to be
assessed:
- risk from access by animals, birds or
insects which may result in transfer of MBM outside the
store, and in the case of some animal species, a possible
risk of BSE.
The actual risk of rodents (at least
mice) acquiring BSE from consuming potentially BSE-infected
MBM appears to be remote. Even in studies where two strains
of mice were fed BSE-infected bovine brain material, only
one of these developed a TSE after the consumption (on
average) of 9g of infected bovine brain (Barlow and
Middleton, 1990)
- risk through access by young children,
vandals, etc. which could lead to escape of MBM and/or the
risk of CJD. Bases on epidemiological studies/information
an estimate can be made for some countries of the
number/ratio of probably BSE-infected carcasses that were
unwittingly processed to provide food for humans. Using
this data, the present risk would appear to be very low
although there is insufficient information to confirm
this.
- Contamination of watercourses due to
poor containment of water used for cleaning storage areas,
vehicles, etc.
- Microbial growth in the MBM, for
example Salmonella (NB: odour problems may also arise This
is unlikely to be a significant issue if exposure to water
is avoided.
- Risks from dust generation to both
reduce workers through MBM inhalation and potential for
escape through doors, etc. (NB: This is also very important
to minimise fire and explosion risk). Risk of fire through
failure to control "core " temperature of stored MBM, which
may result in widespread dispersal of contaminated
material, formation of toxic products and an unpleasant
odour.
Though these risks appear to be very
small, it is appropriate nonetheless to ensure that they
are minimised by having a requirement for:
- good containment of the MBM in a fully
enclosed store which excludes water ingress and egress of
airborne MBM [NB: water contact with MBM enables microbial
growth and enhances the fire risk];
- a well managed secure facility to
ensure that:
-
access is limited to those who need to
be there;
-
all those entering the premises are
well versed in the health and safety requirements;
-
the MBM is turned regularly to reduce
the likelihood of solidification and the build up of
temperature;
-
the premises are well maintained and
animal, bird and insect entry is prevented.
The risk of fire in MBM stores is
illustrated by the experience of auto-combustion with the
release of smoke without flames at two major sites in
Brittany during 1999. In the UK a fire occurred too, in
Preston.
Fire risk is greatly increased if
oxidation of the fat in the MBM occurs. This is not a new
problem for stored material with a substantial fat content
(eg: fish meal). It is recommended that appropriate
anti-oxidants are added routinely and that contact with
water is prevented to minimise the fire risk.
b. Standard of cleanliness
Special arrangements should be in force
for handling and transporting specific risk materials (SRM)
from cattle for disposal, to ensure both worker protection
and appropriate storage and disposal to avoid the material
from entering food and feed chains. The material should be
stained to distinguish it from other products. High
standards of cleanliness should be maintained by all those
coming into contact with SRM including, for example,
hauliers during loading and unloading the material at
abattoirs and rendering plants.
The standard disinfecting process for
many pathogenic materials is to use sodium hypochlorite
solutions. The chemical disinfection of containers,
vehicles, working surfaces, floors etc exposed to
contamination by SRM is not practicable in the case of BSE
due to the resistance of TSE agents to routine methods of
disinfection. An alternative approach for TSEs is to use
hot alkaline solutions of sodium hydroxide. (This is the
subject of an ongoing EU Research Project by Oberth, Piva,
Schreuder and Somerville). If significant contamination by
TSEs is deemed to be possible, all washings should be
subject to further appropriate treatment. Particles of
solid material falling on to the floor or hosed out of
storage bays or hoppers etc should be prevented from
entering drainage systems.
During MBM production and subsequent
transportation or storage as well as any grinding before
disposal, particular emphasis must be given to minimising
dust generation.
Engineering controls should be employed
to enclose processes and minimise handling as much as
possible. Local exhaust ventilation (LEV) equipment fitted
with suitable dust filters may also be of use, for example
at filling and tipping points. Where LEV is used, it is
essential that the captor hood is placed as close as
possible to the source of any potential dust exposure.
Suitable equipment may be fixed or portable so that it can
be removed for maintenance or, for example, clearing of
blockages. It is also important that effective dust traps
are in place to avoid the possibility of any contaminated
material being released into the general
environment.
Methods of loading MBM into and out of
storage sites should be designed to minimise manual
handling and dust generation. Ventilated cabs fitted with
suitable dust filters should be used to provide protection
if there is a risk of possible exposure to dusty
material.
A clear work programme should be drawn
up for the decontamination of individual stores which
should be prepared by a suitably qualified person. A store
will have its own physical characteristics, which should be
taken into account when it is emptied and ready for
cleansing. Potentially difficult areas to access should be
noted and extra care taken here.
All storage areas should be completely
emptied and thoroughly cleansed before further use. It is
recommended that an industrial vacuum cleaner be used to
ensure removal of all gross debris. This reduces the
likelihood of the spread of airborne particles and is
therefore preferred to brushing. Material collected in the
industrial vacuum cleaner must be disposed of with
particular care because of its dusty nature either by
transfer to a rendering plant, or incineration or other
appropriate means of disposal.
Once the loose material has been removed
the entire storage area must be subject to a de-greasing
type operation to remove any melted animal fats. Any wooden
or porous structures in the building must be thoroughly
examined to check if any melted animal fats have penetrated
them. If so, these must be subject to repeated de-greasing
operations to ensure that the melted animal fats have been
removed. The floor, ground, walls and ceilings must be
examined carefully to determine if any rendered material
has penetrated them. Likewise, any drains within the stores
must be opened and inspected to check for the presence of
any rendered material and resealed. If so, appropriate
measures must be undertaken to remove and dispose of such
material.
The storage areas should then be
properly cleansed using strong alkaline solutions where
practicable, disinfected and dried.
Care must be taken to ensure that no
material, either in solid or liquid form, is released into
the environment
. Any solid material recovered during the cleansing
and disinfection should be bagged in a leak-proof and
sealable receptacle, the contents clearly identified, and
stored in a safe place. It should be kept separated from
any other material to prevent contamination and then
disposed of in accordance with guidelines for handling
specified risk materials (SRMs).
All equipment used for handling the
rendered material (prior to and during the cleansing) must
be properly cleaned using appropriate cleansing or
sanitising agents, disinfected and dried,
before it is used for any other purpose. Material
removed from the equipment should be handled as indicated
in the preceding paragraph.
Protective clothing used whilst handling
rendered material should be bagged before removal from the
site or if contamination is assessed to be minimal
thoroughly washed with hot water and detergent before
re-use.
c. Effective measures for the protection of
workers
Although much ofthis opinion is centred
on issues relating to the storage of MBM, it should be
remembered that a number of other groups of workers are
required to handle SRM derived materials and may require
similar protection measures, eg:
-
Incineration plants - which may
destroy MBM by incineration;
-
Rendering plants - which produce MBM
and may use it as a fuel in the rendering process
-
Hauliers - that load and transport MBM
from the renderers to, for example, storage sites.
-
Abattoir workers.
To date, there have been no confirmed
cases of occupational transmission of BSE and none of the
cases of vCJD have any obvious occupational links with
exposure to BSE
). Thus UK figures indicate that while several of
the vCJD cases occurred among workers in animal farming or
the meat industry, in percentage terms the incidence among
these groups of workers did not differ from the percentage
in a control population (UK Annual Report of Committee of
Dangerous Pathogens, 1999.). Nonetheless it is necessary to
ensure that all appropriate means of worker protection are
in place. The following recommended controls are based on
those introduced in the UK.
As part of their risk assessment, those
managing storage facilities that are working with MBM
should consider the potential routes of exposure. There is
no evidence that the BSE agent can infect animals by the
airborne route (although this cannot be ruled out entirely)
but it has been shown to infect by the oral route.
Nonetheless, minimising exposure to aerosols and dusts is
prudent and in keeping with the principles of good
occupational hygiene. The most likely other routes of entry
are by dusty material contaminating wounds and open lesions
on the skin, splashing of mucous membranes (eyes and mouth)
or possibly by accidental ingestion. Basic precautions
which should be taken to avoid contact between MBM and
human mucous membranes are: [taken from BSE: Background and
general occupational guidance HSE, UK].
-
Personal contamination by splashing
should be avoided by using waterproof protective clothing
including gloves and face-shield when, for example,
hosing out a vehicle after delivery of SRM or at the site
where it is received or when carrying out maintenance
work on plant. Protective clothing should be removed
before entering the cab of a vehicle or doing other work
and before taking meal breaks etc. Protective clothing
should be kept apart from other clothing and cleaned by
washing thoroughly and regularly.
-
If splashed in the eyes or face, wash
with running water.
-
Taking steps to avoid the generation
of aerosols and dusts. If dust generation is possible,
face-shields must be worn.
-
Washing hands and exposed skin before
eating/drinking/smoking, taking any medication, using the
telephone or going to the toilet.
-
Adherence to safe working practices
and take extra care to avoid or minimise the use of tools
or equipment likely to cause cuts, abrasions or puncture
wounds.
-
Covering existing cuts, abrasions and
skin lesions on exposed skin with waterproof
dressings.
-
If cuts or puncture wounds occur,
encourage the wound to bleed, then wash thoroughly with
soap and water and cover with a waterproof
dressing.
d. Safe transport
When loaded, all haulage vehicles need
to be tightly secured and sealed with robust covers to
prevent spillage during transportation. Once in place the
covers should only be loosened and removed at the
destination storage or disposal point.
Effective measures that follow the
principles set out above need to be in place to deal with
spillages, particularly during the loading and unloading of
vehicles. This process should always be conducted in a
controlled area.
Any vehicle used for the carriage of the
rendered material must not be used for the carriage of
other material until properly cleaned out using an
industrial vacuum cleaner, cleansed using appropriate
cleansing or sanitising agents, disinfectedand
dried.
The load sheet(s) for the vehicle must
be included in any cleansing and disinfection routine. If
there is a significant risk of the load sheets being
contaminated with
BSE material, the sheets must be disposed of by
appropriate means. Particular care should be taken to
cleanse and disinfect the blower unit on the blower
vehicles, the delivery pipe and the wheels. No vehicle
should be used for the transport of any other material
unless it is inspected at the time of loading and found to
be clean and dry. Collected material must be disposed of by
appropriate means
Fully detailed documentary records of
the procedures undertaken to cleanse sites following the
removal of the rendered material should be kept.
For vehicles, written confirmation of
when and where cleansing and disinfection took place,
together with the identity of the vehicle/trailer, should
be obtained and the records retained.
It is recommended that the local
authority and/or government agency also confirms that it is
content with the standard of cleansing, which will help to
inspire confidence in future potential store users and
demonstrate that the site will not cause pollution or harm
to human health.
References.
Barlow, R.M., Middleton; D.J., 1990. Dietary
transmission of Bovine Spongiform Encephalopathy. Vet.
Record,
126: 111-112.
UK. BSE (Bovine spongiform encephalopathy):
Background and general occupational guidance.
Guidance for handling meat and bone meal material.
UK Advisory Committee on Dangerous Pathogens, HSE, ISBN
0717612120.
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