TOPIC : Standardisation in Synthetic Biology (CSA)
|Publication date:||27 October 2017|
|Types of action:||CSA Coordination and support action|
|DeadlineModel: Opening date:||single-stage 31 October 2017||Deadline:||22 February 2018 17:00:00|
|Time Zone : (Brussels time)|
Topic DescriptionSpecific Challenge:
Systems biology and synthetic biology are scientific fields with potential to transform our way to understand and interact with nature. Synthetic biology combines knowledge and tools from biology and engineering for the design of biological systems that are thus programmed to do what we want them to do, be it for pharmaceutical products (e.g. active pharmaceutical agents or enzymes), in the environment (e.g. bio-pesticides), or industry (e.g. biochemicals).
Standardisation in electric and mechanical engineering has underpinned the success of global industrial production. However, the question remains about how much of this can be imported into the biological domain. Standards for the biological components used by synthetic biology will facilitate creating the blueprint of a given component with identical representation methods. This could bring major advancement in biotechnology and strengthen European leadership in future biotechnological research and production.Scope:
Proposals will be based on equivalent standardisation experiences that can be imported into the biological realm along with a thorough analysis of the functions of live systems that can be amenable to standardisation, generating new approaches where previous experiences do not apply. It will involve a dialogue with experts of the relevant disciplines on the necessary steps to set up principles for understanding, measuring, refining and, to the extent possible, standardizing the engineering of biological systems in support of their broad application in different industrial sectors. Standardisation will be considered in the following fronts: designation of the component/part, specifications, methodologies involved and assembly. Proposals will take into consideration worldwide actions to create synergies and partnerships between leading EU and international scientists, engineers and industrialists.
Proposals will include Social Sciences and Humanities (SSH) elements regarding the ethical dimensions and the environmental impact of products issued from synthetic biology research.
In line with the strategy for EU international cooperation in research and innovation (COM(2012)497), international cooperation is particularly encouraged.
Proposals submitted under this topic should include actions designed to facilitate cooperation with other projects; to enhance user involvement; and to ensure the accessibility and reusability of data produced in the course of the project.
The Commission considers that proposals requesting a contribution from the EU up to EUR 2 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.Expected Impact:
- A list of the most urgent standardisation needs via current practice leading to homogeneity in research and production;
- Identified scientific research gaps whose elucidation would accelerate standards-driven biological engineering;
- A realistic strategy based on research programmes, resources, facilities and structures needed to sustainably support the establishment of and compliance with standards for synthetic biology in the EU in the medium to long term.
Topic conditions and documents
1. Eligible countries: described in Annex A of the Work Programme.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon 2020 projects. See the information in the Online Manual.
Proposal page limits and layout: please refer to Part B of the proposal template in the submission system below.
- Evaluation criteria, scoring and thresholds are described in Annex H of the Work Programme.
- Submission and evaluation processes are described in the Online Manual.
The following exceptions apply:
Under 3 (a) Proposals are first ranked in separate lists according to the topics against which they were submitted (‘topic ranked lists’). When comparing ex aequo proposals from different topics, proposals having a higher position in their respective 'topic ranked list' will be considered to have a higher priority in the overall ranked list.
Under 3 (b) For all topics and types of action, the prioritisation will be done first on the basis of the score for Impact, and then on that for Excellence.
4. Indicative time for evaluation and grant agreements:
Information on the outcome of evaluation (single-stage call): maximum 5 months from the deadline for submission.
Signature of grant agreements: maximum 8 months from the deadline for submission.
5. Proposal templates, evaluation forms and model grant agreements (MGA):
Coordination and Support Action:
6. Additional provisions:
Members of consortium are required to conclude a consortium agreement, in principle prior to the signature of the grant agreement.
8. Additional documents:
1. Introduction WP 2018-20
5. Introduction to Leadership in enabling and industrial technologies (LEITs) WP 2018-20
5ii. Nanotechnologies, advanced materials, advanced manufacturing and processing, biotechnology WP 2018-20
7. Open access must be granted to all scientific publications resulting from Horizon 2020 actions.
Where relevant, proposals should also provide information on how the participants will manage the research data generated and/or collected during the project, such as details on what types of data the project will generate, whether and how this data will be exploited or made accessible for verification and re-use, and how it will be curated and preserved.
Open access to research data
The Open Research Data Pilot has been extended to cover all Horizon 2020 topics for which the submission is opened on 26 July 2016 or later. Projects funded under this topic will therefore by default provide open access to the research data they generate, except if they decide to opt-out under the conditions described in Annex L of the Work Programme. Projects can opt-out at any stage, that is both before and after the grant signature.
Note that the evaluation phase proposals will not be evaluated more favourably because they plan to open or share their data, and will not be penalised for opting out.
Open research data sharing applies to the data needed to validate the results presented in scientific publications. Additionally, projects can choose to make other data available open access and need to describe their approach in a Data Management Plan.
Projects need to create a Data Management Plan (DMP), except if they opt-out of making their research data open access. A first version of the DMP must be provided as an early deliverable within six months of the project and should be updated during the project as appropriate. The Commission already provides guidance documents, including a template for DMPs. See the Online Manual.
Eligibility of costs: costs related to data management and data sharing are eligible for reimbursement during the project duration.
The legal requirements for projects participating in this pilot are in the article 29.3 of the Model Grant Agreement.
No submission system is open for this topic.
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