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TOPIC : A COMPREHENSIVE ‘PAEDIATRIC PRECLINICAL POC PLATFORM’ TO ENABLE CLINICAL MOLECULE DEVELOPMENT FOR CHILDREN WITH CANCER

Topic identifier: IMI2-2015-07-05
Publication date: 18 December 2015

Types of action: IMI2-RIA Research and Innovation action
DeadlineModel:
Opening date:
two-stage
18 December 2015
Deadline:
2nd stage Deadline:
17 March 2016 17:00:00
06 September 2016 17:00:00

Time Zone : (Brussels time)
  Horizon 2020 H2020 website
Pillar: Societal Challenges
Work Programme Year: H2020-JTI-IMI-2016
Work Programme Part: IMI2 Work Plan 2016
Topic Description
Specific Challenge:

Paediatric cancer:

20% of all paediatric cancer remains incurable

Long term side effects associated with treatment

Cancer is often much more advanced, i.e., metastatic, in children then adults

Effective and safe treatments are urgently needed

Scope:

Build a comprehensive translational network of PDX models, matching cell lines/organoids and genetically modified mouse models with complete molecular characterization and proven relevance to major solid paediatric tumours.

Expected Impact:

Increasing the number of cures across a wide range of paediatric cancer histologies (more lives saved);

Potentially mitigating the long term health effects typically associated with conventional chemotherapeutic, better quality of life

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    Summary of the most relevant provisions for participating in IMI2 actions
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    Standard proposal template
    Standard evaluation form
    IMI2 Model Grant Agreement
    Template for Essential Clinical Trials Information
     

 

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