Evaluation of the availability and applicability of computational approaches in the safety assessment of nanomaterials: Final report of the Nanocomput project
Silica nanoparticles JRC scientists demonstrated the effect of silica nanoparticle agglomeration on the level and mechanism of their uptake by cells, i.e. agglomerated particles accumulated more in cells than non-agglomerated ones and presented a modified mechanism of cellular internalisation.
Silica nanoparticles (NPs) are increasingly present in variety of consumer products including cosmetics and food supplements.
They are in development for diverse medical applications such as drug delivery systems, tissue engineering and biosensors.
JRC scientists investigated the in vitro response of cells to nanoparticulate silver.
The study showed how a commonly used assay for detecting pro-inflammatory response can be falsified by the presence of the metallic silver itself.
Silver nanoparticles (Ag NP) are amongst the most commonly used nanomaterials (NMs) in consumer products and much research has been focused on elucidating their potential impact on human health.
The potential of Ag NPs to induce cytotoxicity, genotoxicity, or proinflammatory responses was investigated in many in vitro cell studies.
View of the X-ray photoelectron Spectrometer (XPS) analysis chamber JRC scientist contributed to the functionalisation and characterisation of silicon carbide nanoparticles (SiCNPs).
These particles have the promising potential to be used in cellular imaging applications for improved cancer diagnosis.
With the increase in life expectancy, cancer has become one of the most important health issues around the world.
Treatment efficacy correlates with early and accurate diagnosis. Thus continual improvement is necessary in diagnosis techniques, particularly in imaging.
