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Evaluation of the availability and applicability of computational approaches in the safety assessment of nanomaterials: Final report of the Nanocomput project
©EU
Publication Year: 
2017
JRC Publication N°: 
JRC106386
Authors: 
WORTH Andrew
ASCHBERGER Karin
ASTURIOL BOFILL David
BESSEMS Joseph
GERLOFF Kirsten Britta
GRAEPEL Rabea
JOOSSENS Elisabeth
LAMON Lara
PALOSAARI Taina
RICHARZ Andrea
Male thyroid anatomy Male thyroid anatomy
©Fotolia,Cliparea.com
Jul 04 2017

The JRC's EURL ECVAM has launched a validation study to assess in vitro methods for the detection of chemicals which disrupt thyroid function.

There is global concern about substances, natural and man-made, which have the potential to interfere with the endocrine system.

The thyroid’s main role in the endocrine system is to regulate metabolism through the action of thyroid hormone, by extracting iodine from the blood and incorporating it into thyroid hormones.

Publication Year: 
2017
JRC Publication N°: 
JRC106550
Authors: 
CASATI Silvia
hiPSC neurons and glia hiPSC neurons and glia
©EU, 2017
Jun 26 2017

JRC scientists have published a written protocol, accompanied by a video demonstration for the differentiation of human pluripotent stem cells into neurons and glia.

This new tool should increase reproducibility in laboratory procedures through visual learning.

The Journal of Visualized Experiments (JoVE) has responded to a universally experienced problem within the world of biomedical science to reproduce the results of other labs (today only 10-30% of published scientific articles can be successfully reproduced).

Publication Year: 
2017
JRC Publication N°: 
JRC101481
Authors: 
KAEMPFER Angela
LA SPINA Rita
GILLILAND Douglas
VALZACCHI Sandro
ASTURIOL BOFILL David
STONE Vicki
Reduction of animal tests for the quality control of veterinary vaccines: VICH releases two new guidelines Reduction of animal tests for the quality control of veterinary vaccines: VICH releases two new guidelines
©EU, 2017
May 31 2017

JRC scientists supported the development of two guidelines released by the International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products (VICH) on the harmonisation of criteria to waive target animal batch safety tests for inactivated and live veterinary vaccines. Their implementation (from May 2018 onwards) is a major step towards international harmonisation and will reduce the number of animals used for batch release testing.

JRC Summer School on Alternative Approaches for Risk Assessment JRC Summer School on Alternative Approaches for Risk Assessment
©EU, 2017
May 23 2017

From 16 to 19 May, the JRC hosted in Ispra (Italy) 101 postgraduate students and early-career scientists from 29 countries worldwide for the JRC Summer School on Alternative Approaches for Risk Assessment.

Publication Year: 
2017
JRC Publication N°: 
JRC102762
Authors: 
HAMM Jon
SULLIVAN Kristie
CLIPPINGER Amy J.
STRICKLAND Judy
BELL Shannon
BHHATARAI Barun
BLAAUBOER Bas J
CASEY, Warren
DORMAN David
FORSBY A.
GARCIA-REYERO Natàlia
GEHEN Sean
GRAEPEL Rabea
HOTCHKISS John
LOWIT Anna
MATHESON Johanna
REAVES Elisa
SCARANO Louis
SPRANKLE Cathy
TUNKEL Jay
WILSON Dan
XIA Menghang
ZHU Hao
ALLEN David
Expert survey on identification of gaps in available test methods for evaluation of endocrine disruptors
©EU
Publication Year: 
2017
JRC Publication N°: 
JRC106244
Authors: 
BOPP Stephanie
NEPELSKA Malgorzata
HALDER Maria Elisabeth
MUNN Sharon
Reducing animal testing while improving the safety assessment of chemicals for skin allergies Reducing animal testing while improving the safety assessment of chemicals for skin allergies
©taborsky - Fotolia.com
May 03 2017

The JRC's European Union Reference Laboratory for alternatives to animal testing (EURL ECVAM) has published its recommendation on the use of non-animal approaches for skin sensitisation (allergy) testing.

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