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  1. A cross-sector review of the demand for in vivo carcinogenicity studies

    29 Jun 2016 The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre releases its report reviewing the current demand for in vivo carcinogenicity studies across chemica ...

    29 June 2016

  2. Summary records available for the meeting of EURL ECVAM with its stakeholders and regulatory advisory network

    21 Jun 2016 The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) has published the summary records for the meetings which took place with the members of the Preliminary Assessment of Regulatory Relevance (PARERE) network ...

    21 June 2016

  3. EURL ECVAM hosts meeting of European 3Rs Centres

    08 Jun 2016 From 31 May to 1 June 2016, the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre hosted a second meeting of European 3Rs Centres at the JRC site in Ispr ...

    08 June 2016

  4. EURL ECVAM training on modern toxicological sciences

    31 May 2016 On 18-19 May 2016 EURL ECVAM ran a training course on "Basic knowledge in modern toxicological sciences" designed for students of Master’s programmes of Toxicology.  23 students from 12 different countries participated in the course ...

    31 May 2016

  5. Avoiding chronic fish toxicity testing

    17 May 2016 The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre has just released its report presenting scientific options for avoiding chronic fish testing on the ...

    17 May 2016

  6. EU and Brazil strengthen international cooperation on alternatives to animal testing

    04 May 2016 From the 5 th to 8 th April 2016, four representatives from the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) of the European Commission's Joint Research Centre (JRC) undertook a mission to promote al ...

    04 May 2016

  7. Review of case studies on the human and environmental risk assessment of chemical mixtures

    Humans and wildlife can be exposed to an infinite number of different combinations of chemicals in mixtures via food, consumer products and the environment, which might impact health. The number of chemicals and composition of chemical mixtures one might ...

    29 June 2016

  8. Analysis of carcinogenicity testing for regulatory purposes in the European Union

    The approaches for evaluating the carcinogenic potential of substances, including whether carcinogenicity studies should be conducted, differ substantially across sectors. Despite variations in testing schemes, the two-year bioassay study in rodents repre ...

    29 June 2016

  9. SEURAT: Safety Evaluation Ultimately Replacing Animal Testing – Recommendations for future research in the field of predictive toxicology

    The development of non-animal methodology to evaluate the potential for a chemical to cause systemic toxicity is one of the grand challenges of modern science. The European research programme SEURAT is active in this field and will conclude its first phas ...

    19 June 2016

  10. Screening methodology to identify potential endocrine disruptors according to different options in the context of an impact assessment

    Several pieces of EU legislation regulate the marketing and use of chemical substances. While several regulations, including the regulations on Plant Protection Products (PPPR), Biocidal Products (BPR) and Chemicals (REACH), include provisions for endocri ...

    17 June 2016

  11. A surface plasmon resonance sensing method and sensing system

    A SPR sensing method comprising the steps of: providing a SPR sensor comprising a SPR supporting sensor surface and contacting a sample to be analysed with the sensor surface. At least one resonance condition at said SPR supporting sensor surface is monit ...

    20 May 2016

  12. Assessing eco-innovations in green chemistry:Life Cycle Assessment (LCA) of a cosmetic product with a bio-based ingredient

    Due to the growing interest in assessing the environmental impacts of cosmetic products, research and development activities try enhancing and promoting eco-innovation solutions in cosmetic industry. This study is aimed at comparing the environmental prof ...

    12 June 2016

  13. Techno-economic and environmental evaluation of CO2 utilisation for fuel production. Synthesis of methanol and formic acid

    The present report assesses the technological, economic and environmental performances for producing methanol and formic acid from carbon dioxide. Methanol and formic acid are well known chemicals that can be used in the future transport sector and as hyd ...

    18 June 2016

  14. Safety of tattoos and permanent make-up State of play and trends in tattoo practices

    The European Commission launched the 18-month project "Tattoos and Permanent Make-up" with the aim of collecting data about the use, the ingredients, the EU market and possible health problems associated to tattoo and permanent make-up (PMU) ink ...

    29 May 2016

  15. Scientific options for avoiding chronic fish testing on the basis of existing data and extrapolation approaches

    The assessment of aquatic toxicity is an important component of the environmental hazard and risk assessment of all types of chemicals, and is therefore included in several pieces of EU chemicals legislation. Aquatic toxicity refers to the effects of chem ...

    13 May 2016

  16. “Watching the Detectives” report of the general assembly of the EU project DETECTIVE Brussels, 24–25 November 2015

    SEURAT-1 is a joint research initiative between the European Commission and Cosmetics Europe aiming to develop in vitro- and in silico-based methods to replace the in vivo repeated dose systemic toxicity test used for the assessment of human safety. As on ...

    08 June 2016

  17. Scoping report on the potential impact of on-board desulphurization on the water quality in SOx Emission Control Areas

    The input of acid substances (like SO2) into the sea has been recognized as an environmental issue that needs to be considered in terms of ocean acidification; acid inputs and techniques to deal with them have implications for member states' obligati ...

    13 May 2016

  18. Public Launch Conference: Information Platform for Chemical Monitoring (IPCHeM)

    19 Oct 2015 The public launch of IPCheM, the Information Platform for Chemical Monitoring, will take place on Monday, 19 October 2015, in Brussels. IPCheM is a single access point for locating and retrieving chemical monitoring data collections. Supportin ...

    14 October 2015

  19. Entrepreneurship- from ideas to success

    24 Sep 2015 to 25 Sep 2015 The JRC is organising this workshop under the Microbial Community-based sequencing analysis linked to anthropogenic pressures (MicroCoKit), within the framework of the FP7 Marie Curie Action: "Industry Academia Partnerships ...

    01 September 2015

  20. Guidance for the identification of polymers in multilayer films used in food contact materials: User guide of selected practices to determine the nature of layers

    This guidance describes how to characterize the composition of a multilayer plastic film for food packaging, with respect to the consecutive order of the layers and their identity. It provides necessary background information on the general composition of ...

    15 April 2016

  21. Precision criteria of methods for the quantification of metals migrated from Food Contact Materials: Pre-validation data derived from ILCs on elements representative for plastics and ceramics

    Precision criteria for the quantification of metals in acetic acid 3% and acetic acid 4% migration solutions for different analytical techniques were calculated and are presented in this report. They were derived from two interlaboratory comparisons (ILC0 ...

    13 April 2016

  22. A global approach towards alternatives to animal testing

    17 Nov 2015 Members of the International Cooperation on Alternative Test Methods attended a two-day meeting hosted by the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) on 10-11 November 2015 at the JRC's Ispra si ...

    17 November 2015

  23. Environmental sustainability assessment of bioeconomy value chains

    Bioeconomy has gained political momentum since 2012 when the European Commission adopted the strategy “Innovating for Sustainable Growth: A Bioeconomy for Europe”. Assessing the environmental performance of different bioeconomy value chains (divided in th ...

    25 May 2016

  24. Adverse Outcome Pathways for Regulatory Applications: Examination of Four Case Studies With Different Degrees of Completeness and Scientific Confidence

    Adverse outcome pathways (AOPs) offer a pathway-based toxicological framework to support hazard assessment and regulatory decision-making. However, little has been discussed about the scientific confidence needed, or how complete a pathway should be, befo ...

    10 April 2016

  25. Assessing the combined effects of chemicals using non-animal methods

    20 Oct 2015 Novel, non-animal tools and scientific methodologies show high potential for the assessment of combined effects of chemicals on humans and the environment. They allow meaningful information on individual mixture components or whole mixtures to ...

    20 October 2015