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  1. Determination of brominated flame retardants: a proficiency test

    JRC conference contribution presenting the results of a proficiency test for the determination of total bromine and several polybrominated biphenyls and diphenyl ethers (PBB and PBDE) in plastic. This manuscript presents the results of a proficiency test ...

    30 April 2014

  2. IMEP-34: Heavy Metals in Toys according to EN 71-3:1994

    JRC Scientific and Technical Research Report presenting the results of an  interlaboratory comparison (ILC) which focussed on the determination of soluble antimony (Sb), arsenic (As), barium (Ba), cadmium (Cd), chromium (Cr), lead (Pb), mercury (Hg), and ...

    30 April 2014

  3. Chapter 3: Analytical Quality Assurance

    A JRC authored book chapter providing an overview which covers basic aspects relevant to quality with a special focus on analytical quality in the field of food analysis. Thousands of analytical measurements are performed every day in food laboratories al ...

    30 April 2014

  4. Programme of pre-accession assistance "Improving Chemical and Ionising Radiation Metrology" in Turkey- Fourth Interim Report

    JRC Scientific and Technical Research Report providing  an overview on progress of the project Europe and Metrology in Turkey (EMIT). The aim of the project is to contribute to the better functioning of the EU-Turkey Customs Union Agreement. The report re ...

    30 April 2014

  5. From the packet to the pan: keeping harmful chemicals out of your food

    Examples of JRC research making the life of Europe's citizens safer and more secure in the area of food safety. (2009) 2009 Leaflets Health and consumer protection food/feed safety quality chemical IHCP IRMM jrc_leaflet_food_materials_de.pdf jrc_leaf ...

    30 April 2014

  6. Validation of Dynamic Light Scattering and Centrifugal Liquid Sedimentation Methods for Nanoparticle Characterisation

    A variety of techniques exists to analyse the size and size distribution of nanoparticles in a suspension. However, neither full method validation reports nor suitable reference materials with properly assigned values traceable to SI are easily found in t ...

    30 April 2014

  7. Functional analysis of the integration host factor site of the sigma54 Pu promoter of Pseudomonas putida by in vivo UV imprinting

    The integration host factor (IHF) of Pseudomonas putida connects cell growth to transcriptional activity of distinct promoters. The IHF site of the sigma54 promoter Pu of the TOL (m-xylene biodegradation) plasmid pWW0 of P. putida has been examined to def ...

    30 April 2014

  8. Numerical and Experimental Methodology for the Development of a New Membrane Prototype Intended to Microfiltration Bioprocesses. Application to Milk Filtration

    In tangential flow filtration, the non-uniform TransMembrane Pressure (TMP) on the membrane length produces a non homogeneous filtration cake, initiates process selectivity changes and modifies the permeate quality. The purpose of this study is to create ...

    30 April 2014

  9. Proficiency testing in analytical chemistry, microbiology and laboratory medicine: working discussions on current practice and future directions

    A summary of the working group (WG) discussions on proficiency testing (PT) and external quality assessment (EQA) held at the EURACHEM Workshop, Istanbul, 3?6 October 2011, is provided. The six WGs covered a range of issues concerned with current practice ...

    30 April 2014

  10. Nanotechnology in manufacturing paints for eco-efficient buildings

    The addition of a photocatalyst provides decontamination properties to a paint. It is able of continuously oxidizing both organic and inorganic pollutants and microorganisms under the influence of light. Photocatalytic paints are useful in a wide range of ...

    30 April 2014

  11. Training needs for toxicity testing in the 21st century: a survey-informed analysis

    Current and future training needs on the use of alternative methods in predictive toxicology, including new approaches based on mode of action (MOA) and adverse outcome pathway (AOP) concepts, are expected to evolve rapidly. In order to gain insight into ...

    30 April 2014

  12. Can acute dermal systemic toxicity tests be replaced with oral tests? A comparison of route-specific systemic toxicity and hazard classifications under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)

    Acute systemic toxicity data (LD50 values) and hazard classifications derived in the rat following oral administration and dermal application have been analysed to examine whether or not orally-derived hazard classification or LD50 values can be used to d ...

    30 April 2014

  13. Climate-based archetypes for the environmental fate assessment of chemicals

    Emissions of chemicals have been on the rise for years, and their impacts are greatly influenced by spatial differentiation. Chemicals are usually emitted locally but their impact can be felt both locally and globally, due to their chemical properties and ...

    30 April 2014

  14. EURL ECVAM progress report on the development, validation and regulatory acceptance of alternative methods (2010-2013)- Prepared in the framework of Directive 76/768/EEC and Regulation (EC) No 1223/2009 on cosmetic products

    Provisions of Regulation No 1223/2009 on cosmetic products require that the European Commission reports on a yearly basis to the European Parliament and Council on the progress made in the development, validation and regulatory acceptance of alternative m ...

    30 April 2014

  15. EURL ECVAM Recommendation on the 3T3 Neutral Red Uptake Cytotoxicity Assay for Acute Oral Toxicity Testing

    Acute oral toxicity is currently being assessed by a suite of refinement test methods based on the traditional LD50 lethality test and is, besides skin sensitisation, the only remaining animal test required under REACH Annex VII. In view of assessing the ...

    30 April 2014

  16. Key scientific issues relevant to the identification and characterisation of endocrine disrupting substances- Report of the Endocrine Disrupters Expert Advisory Group

    The European Commission, under Directorate-General for Environment (DG ENV) as file leader of the Community Strategy on Endocrine Disrupters, In 2010, DG ENV created an ad hoc group of Commission Services and Member States on the EU Community Strategy on ...

    30 April 2014

  17. ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study

    The potential for a compound to induce carcinogenicity is a key consideration when ascertaining hazard and risk assessment of chemicals. Among the in vitro alternatives that have been developed for predicting carcinogenicity, in vitro cell transformation ...

    30 April 2014

  18. Dual MRI-SPECT agent for pH-mapping

    Alterations in extracellular tissue pH accompany many disease processes, such as cancer, inflammation and infection. In tumours, extracellular pH is often lower than in normal tissue and it can be correlated with prognosis. 1 Therefore, the capability to ...

    30 April 2014

  19. Non-invasive monitoring of cytotoxicity based on kinetic changes of cellular autofluorescence

    A quantitative, non-destructive cellular autofluorescence based in vitro imaging assay has been developed and applied to study the cytotoxicity of Sodium Lauryl Sulfate (SLS) and HgCl2 chemical compounds on Balb 3T3 cell culture. A phenomenological double ...

    30 April 2014

  20. Assessment of the use of substances in hydraulic fracturing of shale gas reservoirs under REACH

    Hydraulic fracturing is a technique that has been applied for stimulation of conventional oil and gas wells in the US since many years. The recent developments in high volume hydraulic fracturing combined with directional/horizontal drilling techniques ha ...

    30 April 2014

  21. Guidance on classification for reproductive toxicity under the globally harmonized system of classification and labelling of chemicals (GHS)

    With a wider remit, the United Nations formulated a classification and labelling system for universal application, the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). The GHS was first published in 2003 (UN, 2003) and subseq ...

    30 April 2014

  22. Influence of sputtering pressure on surface structure and oxygen reduction reaction catalytic activity of thin platinum films

    The work presents a study on the influence of the sputtering pressure on the surface structure and morphology of low Pt loaded electrodes and their electrochemical behaviour toward oxygen reduction reaction (orr) in sulphuric acid solution and polymer ele ...

    30 April 2014

  23. Use of polyaminocarboxylic acids as hydrophilic masking agents for fission products in actinide partitioning processes

    During the partitioning of trivalent actinides from High Active Raffinate (HAR) solutions most processes have to cope with an undesirable co-extraction of some of the fission products. Four hydrophilic complexing agents of the group of polyaminocarboxylic ...

    30 April 2014

  24. RADES an experimental set-up for the characterization of aerosol release from nuclear and radioactive materials

    A new experimental set-up for the characterization of aerosols has been developed, in order to support with experimental data a better understanding of the source term related to Radiological Dispersal Events (RDE's). We have developed this set-up wi ...

    30 April 2014

  25. Air pollutants in office environments and emissions from electronic equipment: a review

    The aim of this review is to evaluate the existing knowledge on the presence of indoor air contaminants in office buildings. The most commonly found chemicals are aromatic compounds (BTEX), linear and cyclic alkanes (hexane, nonane, methyl-cyclohexane, te ...

    30 April 2014