The Joint Research Centre (JRC) is the European Commission's science and knowledge service which employs scientists to carry out research in order to provide independent scientific advice and support to EU policy.
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Alessia Bogni is a scientific project assistant at the Consumer Products Safety Unit of the European Commission's Joint Research Centre. She received a Degree in Molecular Biology in 1998 at the University of Insubria (Italy), and a PhD in toxicology and pharmacology from University of Konstanz (Germany) in 2003.
The Joint Research Centre (JRC) of the European Commission is organising a workshop to discuss the potential impacts Next Generation Sequencing (NGS) technologies could have, specifically, on the current international action plans against Antimicrobial Resistance (AMR), as well as understand the next steps for their development and implementation in this context.
JRC together with a consortium of leading international metrology laboratories counted single DNA molecules in solution using different analytical methods including digital polymerase chain reaction (PCR). The study revealed a good performance of the different methods and confirms the strengths of digital PCR as a major technology in life sciences.
Collaborating within the European Infect-Met consortium, the JRC has validated novel digital PCR detection methods for the bacterium causing Tuberculosis. These methods allow for the evaluation of the performance and control of the quality of quantitative DNA-based methods. Therefore, they have the potential to improve Tuberculosis treatment.