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  1. Reference materials for nanotechnologies

    Nanotechnologies make use of the properties of nanomaterials. Characterising the properties of nanomaterials, and their structure at the nanoscale (1 nm to 100 nm), requires advanced measurement methods. These methods are often complex or new. Certified r ...

    06 May 2014

  2. Nanotechnology

    Nanotechnology is a key enabling technology and has great potential for addressing societal challenges including energy supply and health care. Nonetheless, the use of nanomaterials also raises safety concerns, which need to be addressed in a Europe-wide ...

    30 April 2014

  3. Validation of Dynamic Light Scattering and Centrifugal Liquid Sedimentation Methods for Nanoparticle Characterisation

    A variety of techniques exists to analyse the size and size distribution of nanoparticles in a suspension. However, neither full method validation reports nor suitable reference materials with properly assigned values traceable to SI are easily found in t ...

    30 April 2014

  4. Impact of Engineered Nanomaterials on Health: Considerations for Benefit-Risk Assessment- EASAC Policy Report- JRC Reference Report

    Nanotechnology encompasses the design, characterisation, production and application of materials and systems by controlling shape and size at the nanoscale (nanometres). Nanomaterials may differ from other materials because of their relatively large speci ...

    30 April 2014

  5. A new certified reference material for size analysis of nanoparticles

    A certified reference material, ERM-FD100, for quality assurance of various nanoparticle sizing methods, was developed by the Institute for Reference Materials and Measurements. The material was prepared from an industrially-sourced colloidal silica conta ...

    30 April 2014

  6. Validation of methods for the detection and quantification of engineered nanoparticles in food

    The potential impact of nanomaterials on the environment and on human health has already triggered legislation requiring labelling of products containing nanoparticles. However, so far, no validated analytical methods for the implementation of this legisl ...

    30 April 2014

  7. Nanotechnology in manufacturing paints for eco-efficient buildings

    The addition of a photocatalyst provides decontamination properties to a paint. It is able of continuously oxidizing both organic and inorganic pollutants and microorganisms under the influence of light. Photocatalytic paints are useful in a wide range of ...

    30 April 2014

  8. Low temperature growth of nanocrystalline and ultrananocrystalline diamond films: A comparison

    In this paper the low temperature deposition of nanocrystalline and ultrananocrystalline diamond (UNCD) films is compared and discussed. NCD films were prepared by hot filament chemical vapor deposition from a 1% CH4/H2 mixture, while microwave plasma che ...

    30 April 2014

  9. Engineered nanoparticles: Nanometrology status and future needs within Europe

    Engineered nanoparticles (ENPs) are particles designed and produced to have all external dimensions in the nanoscale (between approximately 1 nm and 100 nm). ENPs and their agglomerates and aggregates have been used in many industrial applications for man ...

    30 April 2014

  10. Nanosafety: How to allay fears over nanomaterials

    Regulating the use an engineering of nanomaterials is problematic owing to scientific uncertainty and controversy over their safety. To pave the way for regulatory approval and to build consumer confidence, the EC's JRC and the European Academies Sci ...

    30 April 2014

  11. Foreword from the Editor: Virtual Special Issue on Nanotechnology Related Papers

    This virtual Special Issue is dedicated to papers published in Food Additives and Contaminants from 2008 to date referring to the topic of Nanotechnology. The papers show not only the application potential of nanotechnology in the food and consumer produc ...

    30 April 2014

  12. Nanopatterned submicron pores as a shield for nonspecific binding in surface plasmon resonance-based sensing

    We present a novel approach to tackle the most common drawback of using surface plasmon resonance for analyte screening in complex biological matrices? the nonspecific binding to the sensor chip surface. By using a perforated membrane supported by a polym ...

    30 April 2014

  13. Docking of Ubiquitin to Gold Nanoparticles

    Protein nano-particle associations have important applications in nanoscience and nanotechnology such as targeted drug delivery and theranostics. However, the mechanisms by which proteins recognize nanoparticles and the determinants of speci?city are stil ...

    30 April 2014

  14. Interaction among plasmonic resonances in a gold film embedding a two-dimensional array of polymeric nanopillars

    Nanostructured surfaces have proven to be effective in controlling the electric field distribution and triggering a series of interesting physical effects. In particular, ordered metallic lattices with a typical size of the same order of magnitude of the ...

    30 April 2014

  15. Plasma Modification of PCL Porous Scaffolds Fabricated by Solvent Casting/Particulate Leaching for Tissue Engineering

    This study points out how the plasma modification of PCL porous scaffolds, produced by Solvent Casting/Particulate Leaching, may enhance their biocompatibility. A C2H4/N2 plasma deposition followed by a H2 plasma treatment was used to increase the hydroph ...

    30 April 2014

  16. Safety Issues and Regulatory Challenges of Nanomaterials

    The report represents a summary of the presentations and discussions of the Symposium on "Safety Issues and Regulatory Challenges of Nanomaterials" organized by four European FP7 Projects (HINAMOX, NANOPOLYTOX, NEPHH, ENPRA) and the Joint Resear ...

    30 April 2014

  17. Production and characterization of antibodies against crosslinked gelatin nanoparticles and first steps toward developing an ELISA screening kit

    Nanotechnologies are finding a growing range of applications in the food sector. Nanoparticles (NPs) are used notably to add vitamins and other nutrients to foods and beverages without affecting taste and color. They are also used to develop new tastes, p ...

    30 April 2014

  18. Reference materials and representative test materials: the nanotechnology case

    An increasing number of chemical, physical and biological tests are performed on manufactured nanomaterials for scientific and regulatory purposes. Existing test guidelines and measurement methods are not always directly applicable to or relevant for nano ...

    30 April 2014

  19. Synthetic Amorphous Silicon Dioxide (NM-200, NM-201, NM-202, NM-203, NM-204): Characterisation and Physico-Chemical Properties

    The European Commission's Joint Research Centre (JRC) provides scientific support to European Union policy including nanotechnology. Within this context, the JRC launched, in February 2011, a repository for Representative Test Materials (RTMs), based ...

    30 April 2014

  20. Quantitative determination of the biodistribution of nanoparticles: could radiolabelling be the answer?

    The increased incorporation of NPs in everyday products has raised many concerns related to potential toxicological effects derived from long term workplace, environmental or consumer exposure. On the other hand, the potential applications of NPs in the b ...

    07 June 2014

  21. Optimization and evaluation of asymmetric flow field-flow fractionation of silver nanoparticles

    Asymmetric flow field-flow fractionation (AF4) in combination with on-line optical detection and mass spectrometry is one of the most promising methods for separation and quantification of nanoparticles (NPs) in complex matrices including food. However, t ...

    30 April 2014

  22. A rule for designing safer nanomaterials: do not interfere with the cellular redox equilibrium

    A comprehensive evaluation of the biological and toxicological effects of nanomaterials is necessary for the design of safe products. Attempts to describe and predict these effects are increasingly taking mechanistic considerations into account, shifting ...

    30 April 2014

  23. Selection of test methods to be included in a testing strategy to predict acute oral toxicity: An approach based on statistical analysis of data collected in phase 1 of the ACuteTox project

    More than 50 different in vitro and in silico methods assessing specific organ- and system-toxicity, such as haemato-, neuro-, nephro- and hepatotoxic ity, as well as intestinal absorption, distribution and metabolism, have been used in the firstphase of ...

    30 April 2014

  24. Measuring Protein Structure and Stability of Protein- Nanoparticle Systems with Synchrotron Radiation Circular Dichroism

    We measure the structural and stability changes of proteins at nanomolar concentration upon interaction with nanoparticles. Using synchrotron radiation circular dichroism (SRCD) we measure a decrease of 6?C in the thermal unfolding of human serum albumin ...

    30 April 2014

  25. Mechanisms of toxicity induced by SiO2 nanoparticles of in vitro human alveolar barrier: effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression and nanoparticles uptake

    An in vitro human alveolar barrier established by the coculture of epithelial human cell line NCI-H441 with endothelial human cell line ISO-HAS-1 was used to evaluate the effects of silicon dioxide nanoparticles (SiNPs) exposure, in the presence or absenc ...

    30 April 2014