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The TRANSURANUS fuel performance code is a key instrument for the thermal, mechanical and neutron-physical analysis of a cylindrical fuel rod in nuclear reactors. Therefore, it combines the interacting phenomena by taking into account all relevant thermal, mechanical and isotopic properties of nuclear fuel – most of them changing during reactor operation or long-term storage. The code is applied for design as well as for licensing of nuclear fuel – by various research centres, universities, nuclear safety authorities and industrial partners across Europe.