EU Science Hub

Towards a streamlined GMO analysis approach

Feb 22 2017

The JRC, in the context of the European GMOval project, coordinated three inter-laboratory studies for the validation of qualitative methods suitable for screening for the presence of GMOs. The results are presented together with the acceptance parameters used during the in-house validation, the method transferability study and the inter-laboratory validation.

With the growing number of GMOs introduced into the market, official testing laboratories see their workload and costs increase significantly. In a period of economic uncertainty, control laboratories face difficulties to cope with this increasing workload and complexity, thus they need cost-effective, reliable, fast and reproducible testing strategies. 

The core task of the JRC hosted European Union Reference Laboratory for GM Food and Feed (EURL GMFF) is the assessment and validation of DNA-based methods for the analysis of GMOs in food and feed products.

Screening is the first step of the analytical workflow and requires methods targeting genetic elements that are common to as many as possible GMOs; in this way the number of tests to be conducted downstream to fulfil the legal requirements is minimised, and the overall costs decreased.

Read more in: F. Debode et al. "Inter-laboratory studies for the validation of two singleplex (tE9 and pea lectin) and one duplex (pat/bar) real-time PCR methods for GMO Detection", Food Control 73 (2017) 452-461, doi:10.1016/j.foodcont.2016.08.037