The JRC's Chemical Safety and Alternative Methods Unit, incorporating the EU Reference Laboratory for alternatives to animal testing (EURL ECVAM), is proud to present the JRC Summer School on 'Non-Animal Approaches in Science'. The aim of the JRC Summer School is to share knowledge and experience on the latest non-animal approaches used in research and testing including in vitro methods and computational modelling. In addition, the intention is to explore the role of the Three Rs (Replacement, Reduction and Refinement of animal experiments) in science today through discussion and debate. The Summer School is specifically tailored for post-graduate students and early-career scientists working in the biosciences and will focus on non-animal methods and technologies and the opportunities and challenges associated with their application in various fields such as regulatory toxicology and biomedical research. The programme will combine lectures from experts in the field with plenty of interactive sessions to encourage exchange of views and facilitate networking among participants. A visit to the EURL ECVAM laboratory is also planned. Participants will be asked to present a poster describing their own studies or interests related to the topics of the Summer School and to actively participate in a series of hot debates!