In a collaborative effort, the JRC and three European partner organisations gathered lacking knowledge necessary to develop predictive in vitro tests that can identify the risk for the development of cumulative dose-dependent cardiotoxicity of cancer patients treated with anthracyclines.
JRC scientists developed a new certified reference material (CRM) to improve the accuracy of methylmercury measurements in food. This CRM (ERM-AE671) consists of isotopically labelled methylmercury with certified values for the isotopic composition. Used as internal standard, it will make the measurements of methylmercury more accurate.
JRC scientists have assessed the influence of different primer and probe chemistries on the accuracy of digital PCR (dPCR) methods for the quantification of viral Ribonucleic Acid (RNA) using an influenza model. The study demonstrated that innovative reverse transcription digital PCR (RT-dPCR) requires careful evaluation of method performance and quality control, but has, under the condition that it is sufficiently well optimised, large potential for accurate quantification of viral RNA.