We are doing science for policy
The Joint Research Centre (JRC) is the European Commission's science and knowledge service which employs scientists to carry out research in order to provide independent scientific advice and support to EU policy.
The JRC has carried out a study of available knowledge on the replacement, reduction and refinement (the 3Rs) of animal procedures used in research and testing to understand how supply of such knowledge can better meet demand. Findings show that although much 3Rs knowledge exists, its sharing can be improved through better coordination, communication and outreach, and by more emphasis on targeted education and training initiatives.
Public survey launched following the European Commission's communication in response to the European Citizens' Initiative "Stop Vivisection".
Novel, non-animal tools and scientific methodologies show high potential for the assessment of combined effects of chemicals on humans and the environment.
The JRC-run EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) has just published its strategy to promote ways of integrating data obtained through non-animal tests with computer models of the human body.
The European Commission today issued a Communication in response to the European Citizens’ Initiative Stop Vivisection.
Female liver cells, and in particular those in menopaused women, are more susceptible to adverse effects of drugs than their male counterparts, according to new research carried out by the JRC.
The JRC has validated and recommended a new method which is not based on animal testing, to identify chemicals that can trigger skin allergies, estimated to affect already 20% of the population in Europe.
The JRC has released a new strategy on how to replace, reduce and refine the use of fish in testing of chemicals’ effect on flora and fauna in water (aquatic toxicity) and chemicals’ uptake and concentration in living organisms (bioaccumulation). Out of the 11.5 million animals used for experimental purposes in the EU (2011 data), cold blooded animals, namely reptiles, amphibians and fish represent 12.4%. In the case of specific testing for toxicological safety assessment, fish represent 18% of the one million animals used.
In support of EU legislation on safety of chemicals, the JRC has published a state-of-the art review of test methods and non-testing (computational) approaches that help promote the replacement, reduction, and refinement of animal experiments - known as the 3Rs - in the safety assessment of chemicals. The report "Alternative methods for regulatory toxicology – a state-of-the-art review" focuses on "non-standard" methods, i.e. those that are not included in current regulatory guidelines.