EU Science Hub

Use of reference materials and the estimation of measurement uncertainty (2018)

Vials of reference materials for the Alzheimer's biomarker Abeta42
Oct 10 2018
Oct 11 2018

This course provides participants with the theoretical basis for the estimation of measurement uncertainty and establishment of traceability. Measurement uncertainty and traceability are essential for the evaluation of measurement results.

Reference materials are key tools for achieving traceability of measurements, proving the accuracy of methods and demonstrating the proficiency of laboratories. This knowledge is applied to the proper selection and use of reference materials.

Topics tackled

Uncertainty estimation

  • What are the basic principles?
  • How to estimate uncertainty from validation data?
  • How can I use reference materials to estimate my measurement uncertainty?

Establishing traceability

  • What do I have to do to make my results traceable?
  • How can I establish traceability with reference materials?

Reference material selection

  • Where can I find reference materials?
  • Which material is the right one for me?

Reference material handling

  • How much of each material must I use?
  • How should I store my materials?
  • How do I correct for moisture?

Reference materials use

  • How can I demonstrate trueness?
  • How can I demonstrate my method proficiency?

Making full use of available information

  • What do the terms on a certificate mean?
  • What can I do with a certification report?

Intensive practice in small groups

This course strongly emphasises practical application of theoretical concepts. To this end, each lecture is accompanied by exercises in small groups (5-6 people) during which the concepts are put into practice. Each group is supported by a trainer who helps in asking the right questions and guides the group to a successful conclusion. About half of the time of the course is devoted to these exercises.

Announcement leaflet

PDF icon 2018-10-10_use of RM_announcement.pdf

Registration closed

The registration is closed as the course is fully booked.