EU Science Hub

Integrating genomics into personalised healthcare: a science-for-policy perspective

My genome: our future - Integrating genomics into personalised healthcare: a science-for-policy perspective
Feb 12 2019
Feb 13 2019
Brussels
(BE)

The JRC will organise a high-level conference titled "Integrating genomics into personalised healthcare: a science-for-policy perspective" on the 12th and 13th of February, 2019.

Register online before 31.01.2019.

This conference will bring together experts from around the world to discuss the potential of genomics in the prevention, diagnostics, and therapy for cancer and the new opportunities it may bring for citizens and patients in the EU

The discussions will also highlight challenges to the implementation and uptake of genomics-based screening and diagnosis in health systems and map the appropriate actions.

The focus will be on supporting patient-centric policies, covering important aspects such as quality assurance, ownership and security of the genetic information produced, ethics and the impact of the genomics market on healthcare systems. 

The conference will promote cross-disciplinary interactions between specialists in genetics and genomics, health professionals, decision-makers, patient organisations and other relevant stakeholders.

The event supports:

  1. The implementation of the Communication on enabling the digital transformation of health and care in the Digital Single Market; empowering citizens and building a healthier society
  2. The Member States' Declaration on joining forces and genomic data to personalise Healthcare.


Conference themes of interest

The conference will be structured into four sessions, reflecting three main themes.

Theme  I. Genomics for health: the breast cancer example

What is "genomics"? How does it apply to health? What's in it for me – as a citizen? 

Starting from the use of genomics, in the field of breast cancer, the theme will stimulate a broader discussion to illustrate the evolution of genetic testing and gene panels, with a particular focus on:

  • How this facilitates bridging the application of whole-genome sequencing into clinical practice.
  • How genomics can support better diagnostics, targeted treatments, disease monitoring and clinical follow-up.

Theme II. The public health perspective

What are the opportunities and challenges of implementing genomics approaches in public health?  Who are the actors, and what are the actions that are needed for this implementation to succeed?

The theme will foster a debate on public health topics like evidence-generating healthcare, harmonisation, reproducibility, data interoperability, quality and security in the context of genomics. 

It will also map out how the process of translating genomic data into the clinical setting could be facilitated, and explain the impact that the genomics market has on healthcare systems.

Theme III. The citizen and patient perspective

How is genomics experienced by people, as patients, consumers, citizens? How will the citizen and the patient be approached and involved? How is the individual's information valued, and who will use and have access to it?
The theme will propose a consideration and reflection on regulatory and ethical challenges with a particular focus on the societal and legal implications for the citizen.  It will highlight the importance of literacy, both from citizens, patients and health professionals, and discuss ways to mobilise citizen engagement.


Conference organiser

European Commission's Joint Research Centre, Retieseweg 11, 2440 Geel, Belgium

Target audience

The conference aims to include a varied, non-scientific audience of about 350 people, including:

  • Policy makers from the relevant European Commission departments (SANTE, CONNECT, JUST, RTD, GROW), the Scientific Advice Mechanism (SAM) and the European Political Strategy Centre (EPSC)
  • Steering Group on health promotion, disease prevention and management of non-communicable diseases (SGPP) and other SANTE working/expert groups
  • National public health authorities
  • Researchers and clinicians
  • Citizens and patients representatives
  • European Medicines Agency and its national equivalents
  • Industry representatives
  • Members of national and EU parliaments

Registration

The number of participants is restricted to 350.

Please register online before 31.01.2019.

Programme

DAY 1

Institutional address

Vladimír Šucha, Director General, European Commission, Directorate-General Joint Research Centre, Belgium

  • Session I:  Setting the stage

What is "genomics"? How does it apply to health? What's in it for me, as a citizen? 

This session will illustrate the evolution of genetic testing and how the application of sequencing technologies led to the discovery of genetic variants and subsequently to the eventual characterisation of disease variants. This ultimately may lead to applications in clinical practice and this session will highlight how genomics can support better diagnostics, targeted treatments, disease monitoring and clinical follow-up.

Chair: Joris Vermeesh, University of Leuven, Belgium
Co-chair: Irene Norstedt, European Commission, Directorate-General for Research and Innovation, Belgium
Rapporteur: Jacques Simard, Université Laval, Canada

Keynote speakers
Ewan Birney, European Molecular Biology Laboratory - European Bioinformatics Institute, United Kingdom
Sir John Burn, Newcastle University, United Kingdom

Moderated panel discussion with:
Peter Devilee, Leiden University Medical Center, The Netherlands
Mark Bale, Genomics England, United Kingdom
Denis Horgan, European Alliance for Personalised Medicine, Belgium
Peter Kapitein, Inspire2live,The Netherlands

  • Session II: Genomics - Opportunities and challenges

What are the opportunities and challenges of implementing genomics approaches in public health? 

This session will discuss concepts such as evidence-generating healthcare, harmonisation, reproducibility, as well as data interoperability, quality and security.

Chair: Giorgio Stanta, University of Trieste, Italy
Co-chair: Marco Marsella, European Commission, Directorate-General for Communications Networks, Content and Technology, Luxembourg
Rapporteur: Rolf Apweiler, The European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI), United Kingdom

Keynote speakers
Jan Korbel, European Molecular Biology Laboratory (EMBL), Germany
Barend Mons, Leiden University Medical Center (LUMC), The Netherlands

Moderated panel discussion with:
Rodrigo Dienstmann, Vall d’Hebron Institute of Oncology (VHIO), Spain
Stefan Fröhling, National Center for Tumor Diseases (NCT), Germany
Serena Scollen, European Life-Science Infrastructure For Biological Information (ELIXIR), United Kingdom

DAY 2

  • Session III: The Public Health perspective

Who are the actors, and what are the actions that are needed for the implementation of genomics in healthcare to succeed?

The session will map how the process of translation of genomics data to the clinical setting could be facilitated, and explain the impact the genomics market has on healthcare systems.

Chair: Tit Albreht, National Institute of Public Health (NIJZ), Slovenia
Co-chair: Elke Anklam, European Commission, Joint Research Centre, Belgium
Rapporteur: Marc Van den Bulcke, Sciensano, Belgium

Keynote speakers
Thierry Philip, Institut Curie and European Organization of Cancer Institutes (OECI), France

Moderated panel discussion with:
Nazneen Rahman, Independent healthcare consultant, United Kingdom
Jacek Gronwald, Pomeranian Medical University (PMU), Poland
Jan-Ingvar Jönsson, Swedish Research Council, Sweden
Laura van't Veer, University of California San Francisco (UCSF), Helen Diller Family Comprehensive Cancer Center, USA

  • Session IV: The Citizen and Patient perspective

How is genomics experienced by people, as patients, consumers, citizens? How will the citizen and the patient be approached and involved? How is the individual's information valued, and who will use and have access to it?

This session will discuss regulatory and ethical challenges and considerations, with a particular focus on the societal and legal implications for the citizen. It will highlight the importance of literacy, both from citizens, patients and health professionals, and highlight the ways to mobilise citizen engagement.

Chair: Peter Goodhand, Global Alliance for Genomics and Health, Canada
Co-chair: (tbc)
Rapporteur: Rita Schmutzler, Uniklinik Köln, Germany

Keynote speakers
Bartha KnoppersMcGill University, Canada
Francesco Florindi, Biobanking and Biomolecular Resources Research Infrastructure - European Research Infrastructure Consortium (BBMRI-ERIC), Austria

Moderated panel discussion with:
Effy Vayena, ETH Zürich, Switzerland
Bettina Borisch, University of Geneva, Switzerland
Jean-Pierre Hubaux, Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland
Andres Metspalu, University of Tartu, Institute of Genomics, Estonia

Final Keynote
Teri Manolio, National Human Genome Research Institute, National Institutes of Health (NIH), USA

Practical information

  • Venue

The conference is held at the NH Brussels Bloom Hotel, Rue Royale 250, 1210 Brussels, Belgium. The hotel is a 15-minute walk from the historic city centre. It has on-site indoor parking and the daily rate is 27€ (24 hours); you can park your car on the level (-1) or (-2), with the latter being more spacious.

Map to locate the NH Brussels Bloom Hotel

NH Brussels Bloom Hotel web site

How to get there?

  • Public transport: Transport networks to Brussels
  • It takes about 20 min from Brussels Zaventem Airport to Brussels North railway station and the train leaves every 10 min.
  • From Brussels North railway station, it's about 15 min walk to the NH Brussels Bloom Hotel. Map
  • From Brussels North railway station, it's about10 min walk through the rue du Progrès to reach the metro line 2 or 6, direction "Simonis" or "Roi Baudouin" at "Rogier". Alight at the metro "Botanique" and walk for 5 min through the Rue Royal until you get to NH Brussels Bloom Hotel, located on your left. Map of the Brussels metro lines

Visit Brussels: https://visit.brussels/en

  • Conference timing

12 February 2019

08:15 - 09:15     Registration
09:15 - 10:00     Institutional address
10:00 - 13:15     Session I: Setting the stage
13:15 - 14:00     Lunch
14:00 - 14:30     Flash talks by EU Innovation winners
14:30 - 17:45     Session II: Genomics - Opportunities and challenges
17:45                  End of day 1 (Refreshments)

13 February 2019

08:45 - 12:00     Session III: The Public Health perspective
12:00 - 13:15     Lunch
12:45 - 13:15     Flash talks by EU Innovation winners
13:15 - 16:30     Session IV: the Citizen and Patient perspective
16:30 - 17:30     Final keynote presentation
17:30                  End of conference

  • Accommodation

Participants are responsible for organising their travel and accommodation in Brussels; the European Commission will not reimburse these expenses.

/jrc/en/file/document/177254List of hotels

offering a reduced rate for a limited number of rooms during the conference, please pay attention to the deadlines.

  • Catering

The European Commission will provide buffet lunches, coffee/tea breaks and water for the participants at the conference premises.

We will not be able to cater for all needs, but different food options will be available on the buffets.

  • Wifi

Wireless internet access will be made available to participants free-of-charge throughout the venue.

Contact

If you have further questions, please contact JRC-genomicsandcancer@ec.europa.eu

Last update: 18 January 2019