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Skin Corrosion: Corrositex

The Corrositex assay can be used to predict the potential of a substance to cause skin corrosion.

The method is based on the amount of time needed for a chemical to break through a biobarrier membrane and interact with an underlying chemical detection system.

The approach has received regulatory approval as a replacement of in vivo skin corrosivity tests for specific classes of chemicals (namely acids, bases and certain derivatives).

The results of the validation study, the ESAC statement and our recommendation will be soon available on TSAR, the Tracking System for Alternative methods towards Regulatory acceptance.

Skin corrosion

Corrositex

Animal testing replacement

Validation study

Validation study outcomes

EURL ECVAM recommendations