EU Science Hub

International Cooperation on Alternative Test Methods (ICATM)

The International Cooperation on Alternative Test Methods, ICATM, is an international cooperation that includes governmental organisations from:

  • the EU (the European Union Reference Laboratory for Alternatives to Animal Testing, EURL ECVAM)
  • US (the Interagency Coordinating Committee on the Validation of Alternative Methods, ICCVAM)
  • Japan (the Japanese Centre for the Validation of Alternative Methods, JaCVAM)
  • Canada (Health Canada)
  • South Korea (the Korean Centre for the Validation of Alternative Methods, KoCVAM)
  • Brazil (the Brazilian Centre for the Validation of Alternative Methods, BraCVAM)
  • China (currently, the Chinese Food and Drug Administration, CFDA, and the Guangdong Center for Disease Control and Prevention).

ICATM partners are working together to promote enhanced international cooperation and coordination on the scientific development, validation and regulatory use of alternative approaches.

A Memorandum of Cooperation (MoC) was signed in 2009 by four of these agencies which formalised the basis of cooperation between them in three critical areas relating to alternatives to animal testing: validation studies, independent peer review of the validation of test methods and the development of formal test method recommendations on alternative testing methods.

While collaborations have existed between these organisations for many years, prior to the signing of the MoC all interactions were largely on an ad hoc informal basis.

Background

Goals and Purposes

Resources