Table 7-6: Natural extracts with positive human data, which are, however, not sufficient to categorise as “established contact allergen in humans”. More detailed information forming the basis of this evaluation can be found in Annex I of this opinion.

INCI name (or, if none exists, perfuming name according to CosIng) in bold; plant part / type of extract (partly indicative) in plain font CAS number Comment Ref.
ACORUS CALAMUS ROOT OIL 84775-39-3 n=7 pos. reactions to “calamus” (199)
CEDRUS DEODARA WOOD OIL 91771-47-0  Rudzki 1976/1986 found 3 / 3 positive reactions (199, 200).
CITRUS AURANTIUM AMARA LEAF OIL 72968-50-4 Several cases in 2 series from 1 centre (199, 200)
CITRUS TANGERINA 223748-44-5 1 case (201)
CYMBOPOGON NARDUS / WINTERIANUS HERB OIL 89998-15-2; 91771-61-8 Several cases in 2 series from 1 centre (199, 200)
ILLICIUM VERUM FRUIT OIL 84650-59-9 Cases of active sensitisation; 34% consecutive patients pos. to 1% (202)
LAVANDULA SPICA 97722-12-8 Several cases in 2 series from 1 centre (199, 200)
LITSEA CUBEBA 90063-59-5 Several cases in 2 series from 1 centre (199, 200)
PELARGONIUM ROSEUM 90082-55-6 2.1% pos. of 1483 patients (203)
ROSMARINUS OFFICINALIS 84604-14-8 3 cases in 2 series from 1 centre (199, 200)
 SALVIA spp. Diverse Several cases in 2 series from 1 centre (199, 200)
TAGETES PATULA 91722-29-1 1 case (aromatherapist) (193)
THYMUS spp. 84929-51-1 4 / 84 pos (199)
VETIVERIA ZIZANOIDES 8016-96-4; 84238-29-9 1 / 200 and 9 / 86 pos. (199, 200)

Source: SCCS,  Opinion on Fragrance allergens in cosmetic products, pages 55-56