Table 4-5: Results with screening agents for contact allergy to fragrance ingredients reported since
1999 in patients patch tested for suspected allergic contact dermatitis: Fragrance Mix “II” (see Table
4-2). The FM II was only conceived in 2005, so results are still sparse). If not given in the publication,
the confidence interval (CI) was calculated from the absolute numbers by the SCCS (§).
Country (Ref.) |
Population |
Year(s) |
No. tested |
Crude % positive (95% CI) |
EU (35) |
Six clinical depts. |
10/2002-06/2003 |
1701 |
2.9
(2.2–3.9)§ |
IVDK, Germany (68) |
Consecutive patients |
01/2005-12/2008 |
35633 |
4.9
(4.7–5.1)§ |
Groningen, Netherlands (44) |
Patients (fragrance allergy suspected) |
04/2005-06/2007 |
227 |
9.3
(5.8–13.8)§ |
Leuven, Belgium (47) |
Consecutive patients |
2005 only |
335 |
2.1
(0.8–4.3)§ |
Spain (49) |
Consecutive patients |
10/2005-06/2008 |
1253 |
0.6
(0.2–1.1)§ |
Denmark (69) on behalf of the DCDG, 2010 |
Consecutive patients |
2005-2008 |
12302 |
4.5
(4.1–4.9)§ |
Source:
SCCS, Opinion on Fragrance allergens in cosmetic products, page 20
|