Table 4-3: Results with screening agents for contact allergy to fragrance ingredients reported since
1999 in patients patch tested for suspected allergic contact dermatitis in Europe: Fragrance Mix “I”
(see Table 4-1). If not given in the publication, the confidence interval (CI) was calculated from the absolute numbers by the SCCS (§).
Country (Ref.) | Population | Year(s) | No. tested | Crude % positive (95% CI) |
---|
Sweden (38) | Consecutive patients | 2000 | 3790 | 6.9 | Hungary (39) | | 1998-1999 | 3604 | 8.2
(7.3–9.1)§ | Czech Republic (40) | | 1997-2001 | 12058 | 5.8
(5.4–6.2)§ | Ljubljana, Slovenia (41) | Consecutive patients | 1989-1998 | 6129 | 5.9
(5.3–6.5)§ | Germany (42) | Consecutive IVDK patients | 1996-2002 | 59298 | 11.3
(11.0–11.5)§ | Germany (43) | Consecutive IVDK patients | 2005-2008 | 36961 | 7.3
(7.0–7.6)§ | Vienna, Austria (16) | Consecutive patients of one clinic | 1997-2000 | 2660 | 9.1
(8.1–10.3)§ | Groningen, Netherlands (44) | Patients (fragrance allergy suspected) | 04/2005-06/2007 | 295 | 5.8
(3.4–9.1)§ | The Netherlands (45) | Consecutive patients | 09/1998-04/1999 | 1825 | 10.6
(9.2–12.1) | The Netherlands (46) | Patients (cosmetic allergy suspected) | 1994-1998 | 757 | 14.8
(12.3–17.5)§ | Leuven, Belgium (47) | Consecutive patients | 1990-2005 | 10128 | 9.1
(8.6–9.7)§ | Coimbra, Portugal (48) | Consecutive patients | 07/1989-06/1999 | 2600 | 10.9
(9.7–12.2)§ | Spain (49) | Consecutive patients | 10/2005-06/2008 | 1253 | 4.5
(3.4–5.8)§ | Sheffield, UK (50) | Consecutive patients | 1994-1995 | 744 | 11.4
(9.2–13.9)§ | St. John’s, London, UK (51) | Consecutive patients | 1980-2004 | 34072 | 7.7
(7.4–8.0)§ | Copenhagen, Denmark (52) | Consecutive patients | 1985-2007 | 16173 | 7.2
(6.8–7.6)§ | ESSCA (53) | Consecutive patients | 2002-2003 | 9663 | 7.1
(6.6–7.6)§ | ESSCA (54) | Consecutive patients | 2004 | 9941 | 7.6
(7.1–8.2)§ | ESSCA (55) | Consecutive patients | 2005-2006 | 18542 | 7.0
(6.6–7.4)§ |
Source:
SCCS, Opinion on Fragrance allergens in cosmetic products, page 18
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