Table 13-3: Fragrance substances categorised as likely contact allergens by combination of evidence.
INCI name (or, if none exists, perfuming name according to CosIng)   CAS number Human evidence: see text EC 3 value (min; %) SAR
 § Substances/natural mixtures were classified as R43, according to the submission by IFRA. The evidence on which this classification was based was not available to the SCCS, so the validity of classification cannot be assessed. Nevertheless, the four substances/substance mixtures should be treated as likely contact allergens. n.a.: not applicable (natural mixture)
 AMBRETTOLIDE    7779-50-2    limited    none    +  
 CARVACROL    499-75-2    limited    none    +  
 Citrus paradisi §    8016-20-4    none    R43    n.a.  
 CUMINALDEHYDE    122-03-2    limited    none    +  
 CYCLOPENTADECANONE    502-72-7    limited    none    +  
 trans-trans-delta-DAMASCONE    71048-82-3    limited    none    +  
 2,4-dimethyl-3-cyclohexen-1-carboxaldehyde §    68039-49-6    none    R43    +  
 DIMETHYLTETRAHYDRO BENZALDEHYDE    68737-61-1    limited    none    +  
 ETHYL VANILLIN    121-32-4    limited    none    +  
 HELIOTROPINE    120-57-0    limited    none    +  
 ISOAMYL SALICYLATE    87-20-7    limited    none    ++  
 ISOLONGIFOLENEKETONE    33407-62-4    limited    none    +  
 Longifolene §    475-20-7    none    R43    +  
 Mentha arvensis §    68917-18-0    none    R43    n.a.  
 METHOXYCITRONELLAL    3613-30-7    limited    none    +  
 METHYL CINNAMATE    103-26-4    limited    none    ++  
 METHYLIONANTHEME    55599-63-8    limited    none    +  
5-METHYL-alpha-IONONE  79-69-6   limited   none   +  
MYRCENE   123-35-3   limited   none   ++  
MYRTENOL   515-00-4   limited   none   +  
NEROL   106-25-2   limited   none   ++  
Nerolidol (isomer not specified)   7212-44-4   limited   none   ++  
NOPYL ACETATE   128-51-8   limited   none   +  
PHYTOL   150-86-7   limited   none   +  
RHODINOL   6812-78-8   limited   none   +  
trans-ROSE KETONE-5   39872-57-6   limited  !   none   ++  

Source: SCCS,  Opinion on Fragrance allergens in cosmetic products, pages 110-111