|
|
|
Ref. |
| ROAT |
|
|
|
| In ethanol 92 % positive |
0.025 μg/cm2 |
observed |
(238) |
| In ethanol 100% positive |
0.125 μg/cm2 |
observed |
(238) |
| PATCH TEST |
|
|
|
| ED10% |
0.0004 μg/cm2 |
estimated |
(238) |
| ED50% |
0.0045 μg/cm2 |
estimated |
(238) |
| Cinnamal |
| ROAT |
|
|
|
| In ethanol no effect |
0.02% |
observed |
(101) |
| In ethanol 44 % positive |
0.1% |
observed |
(101) |
| In ethanol 72 % positive |
0.8% |
observed |
(101) |
| Deodorant matrix 11% positive |
0.26 μg/cm2(0.01%) |
observed |
(103) |
| Deodorant matrix 41% positive |
0.84 μg/cm2(0.032%) |
observed |
(103) |
| Deodorant matrix 82% positive |
2.63 μg/cm2(0.1%) |
observed |
(103) |
| PATCH TEST |
|
|
|
| ED50% |
96 μg/cm2 |
estimated |
(101) |
| No effect level |
0.4 μg/cm2(0.01%) |
observed |
(101) |
| No effect level |
NG (0.002%) |
observed |
(103) |
| HICC |
| ROAT |
|
|
|
| In a cream base ED10% |
4.9 μg/cm2 |
interpolated |
(105) |
| In a perfume (ethanol) ED10% |
1.2 μg/cm2 |
interpolated |
(105) |
| In ethanol 61% positive |
15.3 μg/cm2(3.4-22.2) |
observed |
(224) |
| In ethanol 89% positive |
126.2 μg/cm2(40.5-226.2) |
observed |
(224) |
| In ethanol/water no response |
0.0357 μg/cm2 |
observed |
(263) |
| In ethanol/water ED10% |
0.064 μg/cm2 |
estimated |
(263) |
| In deodorant matrix between 64% to 100% positive |
0.79 μg/cm2(median) |
observed |
(102) |
| PATCH TEST |
|
|
|
| ED10% (95% CI) |
0.662 μg/cm2(0.052-2.35) |
estimated |
(263) |
| ED10% |
0.75 μg/cm2 |
estimated |
(102) |
| ED10% |
0.9 μg/cm229 (7-69) ppm |
estimated |
(224) |
| ED50% (95% CI) |
11.1 μg/cm2(3.41- 33.1) |
estimated |
(263) |
| ED50% (95% CI) |
18.3 μg/cm2(3.41- 33.1) |
estimated |
(102) |
| ED50% (95% CI) |
20 μg/cm2662 (350-1250) ppm |
estimated |
(224) |
| No effect level |
<0.0022 μg/cm2 |
observed |
(263) |
| Hydroxycitronellal |
| ROAT |
|
|
|
| Deodorant matrix 57 % positive |
0.94 μg/cm2(0.032%) |
observed |
(104) |
| Deodorant matrix 71 % positive |
2.94 μg/cm2(0.1%) |
observed |
(104) |
| Deodorant matrix 100 % positive |
9.40 μg/cm2(0.32%) |
observed |
(104) |
| PATCH TEST |
|
|
|
| No effect level |
<0.00012 % (=0.036 μg/cm2)* (*calculated) |
observed |
(104) |
| Isoeugenol |
| ROAT |
|
|
|
| in ethanol 63% positive |
5.6 μg/cm2 |
observed |
(100) |
| in ethanol 42% positive |
2.2 μg/cm2 |
observed |
(264) |
| in ethanol 67% positive |
9.0 μg/cm2 |
observed |
(264) |
| Deodorant matrix 23 % positive |
0.167 μg/cm2 |
observed |
(279) |
| Deodorant matrix 69 % positive |
0.53 μg/cm2 |
observed |
(279) |
| Deodorant matrix 77 % positive |
1.67 μg/cm2 |
observed |
(279) |
| PATCH TEST |
|
|
|
| ED50% (in petrolatum) |
32 μg/cm2 |
estimated |
(100) |
| No effect (in ethanol) |
<0.0005% (0.15 μg/cm2) |
observed |
(264) |
| No effect (in petrolatum) |
<0.4 μg/cm2 |
observed |
(100) |
