Mice
Bock et al., 1975 |
3% in 0.2 ml applied 5x/wk for 56 weeks |
Negative |
~ 0.71 |
| Kurokowa et al., 1984 |
5% in 0.2 ml applied 2x/wk for 51 weeks |
Negative |
~ 0.48 |
| Shamberger, 1972 |
3% in 0.25 ml applied daily for 40 weeks |
Negative |
~ 1.25 |
| Burnett and Goldenthal, 1988 |
3% (+ hair dye base) in 0.5 ml applied twice weekly /two years).
Successive applications made to adjacent areas to minimise skin irritation |
Negative; |
~ 0.71 |
| Klein-Szanto and Slaga, 1982 |
5% in 0.2 ml applied 2x/wk for 25 weeks, no tumours in the control. |
5% tumours |
~ 0.47 |
| Hamster
Marshall et al., 1996 |
3% in 0.1 ml applied 5x/wk for 16 weeks |
Inadequate |
0.43 |
| Collett et al., 2001 |
3.3% [10% carbamide peroxide] in 0.5 ml applied 1x/wk for 34 weeks |
Negative |
0.47 |
