(Data from Procter & Gamble Safety study 2000045 [5.3% strips] and 2000143 [6% strips]. Note: The procedure used is only published as a book chapter (Whelton, 1996). The calculations are based on salivary flow of 0.3 ml/min. The numbers in parenthesis represent exposure based on the daily use of 4 strips.
Table 3.12. Available hydrogen peroxide in the saliva during the first 30 and 60 minutes
| Calculation |
5.3% Strip mg |
6.0% Strip mg |
| 30 min |
30 min |
60 min |
| Mean |
0.43 (1.7) |
0.68 (2.7) |
1.20 (4.8) |
| Mean + 2xSD |
1.6 (6.2) |
1.21 (4.8) |
2.55 (10.2) |
| Median |
0.11 (0.44) |
0.62 (2.5) |
0.99 (4.0) |
| Max observation |
1.6 (6.2) |
1.3 (5.4) |
2.86 (11.4) |
Source:
SCCP
Opinion on Hydrogen peroxide, in its free form or when released, in oral hygiene products (2007), p.46
