Similar term(s): gene mutation, genetic mutation, chromosomal mutation.
Definition:
Any permanent change in the DNA of a cell.
Mutations may be caused by mistakes during cell division, or they may be
caused by exposure to DNA-damaging agents in the environment.
Mutations can be harmful, beneficial, or have no effect. If they occur in
cells that make eggs or sperm, they can be inherited; if mutations occur in
other types of cells, they are not inherited.
Certain mutations may lead to cancer or other diseases.