Although Trento covers a relatively small area of c. 20,000 km2, with a total population of about 0.5 million inhabitants, its performance in innovation is remarkable. With 2.19% of its GDP invested in R&D, the city is for example well above the European average. Recently, Trento has even been ranked as the “world best practice” in the implementation of the concept of smart cities. Such outstanding track records would certainly not have been possible without the many reforms and programmes developed and implemented in Trento over the years. Clearly much work remains to be done. Yet, Trento’s leaders early efforts to trigger the digital transformation of their territory has certainly given the city a head start.