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European Partnership for Alternative Approaches to Animal Testing

Partners and structure

Members of the EPAA and governance.

Project platform

EPAA project platform mandate and governance, ongoing projects, and completed projects.

Awards and grants

Winners of the Refinement Prize and the 3Rs Science Prize, and 3Rs student grants.

Annual conference

Information and reports from the European Partnership for Alternative Approaches to Animal Testing annual conferences.

Activities and events

EPAA events, partners' forum, collaboration for training in non-animal methods in China, and alternative methods video tutorials.

EPAA logo

The European Partnership for Alternative Approaches to Animal Testing (EPAA) aims to replace animal testing by innovative, non-animal testing methods, to reduce the number of animals used and to refine procedures where no alternatives exist or are not sufficient to ensure the safety of substances (the '3R principle'). The partners are pooling knowledge and resources to accelerate the development, validation and acceptance of alternative approaches at national, European and global levels.

The EPAA seeks to bridge the knowledge gap and to facilitate coordination and cooperation via its partners and project platform. It promotes the results via its various European and international activities and events, its annual conference and via its awards and grants that are particularly addressed to young scientists.

Watch the video on the EPAA

EPAA is on Twitter and LinkedIn

News and highlights

About the EPAA

History and rationale

Launched in November 2005 with the support of European Commissioners Verheugen and Potocnik, the EPAA began operations in 2006. It completed a first mandate of 5 years by the end of 2010.

Due to the encouraging results of the EPAA's projects, the mandate has been renewed for 5-year terms since. Priorities of the second mandate included integrated testing strategies (lead theme 2011), and international collaboration on 3Rs (lead theme 2012-2013).

See the 2011-2015 (37 kB) and 2016-2020 (89 kB) action programmes as well as the founding act of EPAA (3Rs Declaration) (85 kB).

The new action programme 2021-2025 (92 kB) focuses on facilitating regulatory acceptance.


The vision of EPAA is the replacement, reduction and refinement (3Rs) of animal use for meeting regulatory requirements through better and more predictive science.

The EPAA vision and mission paper (340 kB)

Previous annual conferences

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Disclaimer: This webpage contains information on past events, such as agendas of annual meetings or workshops, which may contain the names of speakers. If your name is mentioned and you would like us to remove it, please contact