Animal Welfare Information Centre (AWIC) is part of the US Department of Agriculture. It is mandated by the Animal Welfare Act (AWA) to provide information for improved animal care and use in research, testing, teaching, and exhibition.
Alternatives to Animal Testing web site was created to serve as a gateway to alternatives news, information, and resources on the Internet and beyond. Altweb hosts the journal ALTEX: Alternatives to Animal Experimentation, which is the official publication of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT).
Bibliography on Alternatives to Animal Testing (Altbib), is a resource portal for Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing hosted by Specialized Information Services of US National Library of Medicine.
CAAT-Europe (Centre of Alternatives to Animal Testing) – an academic, science based centre within the John Hopkins Bloomberg School of Public Health in the USA and the University of Konstanz in Germany which is dedicated to the promotion of research intoin vitro and other alternative techniques, Three Rs education and information.
CCAC- Canadian Council on Animal Care promotes the application of Three Rs in Canada. Through a website it provides the latest information on the Three Rs, a search tool and a search guide.
Fund for the Replacement of Animals in Medical Experiments (FRAME) is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused. The E-learning resource of FRAME has been set up to provide teachers, school children, students and general supporters with information about the different areas of animal experimentation and with specific resources as to how it can be reduced, refined or replaced.
3Rs-reduction is a new interactive web-site designed to help scientists to improve the design of their animal experiments. Animal experiments are not always well designed, leading to both ethical concerns and a waste of scientific resources. This is a world-wide problem. Training scientists is difficult as there so are few statisticians with a good understanding of laboratory animal science able to provide such training. This new web-site is designed to help scientists to teach themselves the necessary skills. After an introduction on the ethics of animal experimentation, showing that improvements are needed, it goes on to cover choice of experimental units, avoiding bias, power and sample size, controlling variability, types of experimental design, factorial experiments, statistical analysis and publication guidelines. Most sections are followed by a "Test yourself" page of true/false questions. The web-site is free.
German Centre for the Protection of Laboratory Animals (Bf3R) coordinates all associated activities nationwide with the goal of Reducing animal experiments to the necessary minimum and providing the best possible protection for laboratory animals. Furthermore, national and international research activities and a scientific dialogue is encouraged by the work of the Centre. Mission and goals include intensifying research on alternative methods; advice to authorities and research institutions; international harmonisation of alternative methods; research funding of alternative methods; and provision of information to the public and experts. The activities of the German Centre are part of the Animal Welfare Initiative of the Federal Ministry of Food and Agriculture (BMEL) entitled "Minding animals - new ways to improve animal welfare".
Humane Endpoints website, by 3Rs-Centre Utrecht Life Sciences, gives insight into the recognition and application of humane endpoints in rodents. The website contributes to refinement, the prevention of unnecessary suffering in laboratory animals, by offering information, videos and photographs of rodent species. In addition, the website provides free training modules (accessible after registration). The site is currently available in EN, NL and FR. DE and ES will follow soon.
InVitro Jobs - The aim of "InVitroJobs" is to enable researchers to access this branch of research more easily. Alongside the job search portal, the site maintains an up-to-date list of research groups active in the development of animal-free techniques. The primary aims of this list are to advertise job vacancies, to provide students with the opportunity to contact these research groups directly to obtain information for thesis assignments and to promote cooperation, networking and the exchange of ideas between researchers.
NC3Rs: National Centre for Three Rs, UK - A mainly government funded body which provides input to the UK’s Three Rs agenda, carries out research and provides funds for Three R research.
The EURL ECVAM Tracking System on Alternative methods towards Regulatory acceptance (TSAR) is a tool aimed at providing a transparent view on the status of alternative methods as they progress from purely scientific protocols submitted for eventual validation to being actively used in a regulatory context. This tracking system intends to cover all steps, from the initial submission for validation until final adoption by inclusion in the EU legislation and/or related Guidance Documents, when appropriate.
UCDavis Centre for Animal Alternatives Information places special emphasis on disseminating up-to-date information concerning animal alternatives through every level of public and private education. It also seeks to provide investigators who use animals with information on the most current methods for improving all aspects of animal care during their work.