PSYCHOSOCIAL AND PSYCOBIOLOGICAL APPROACH TO PREVENT AGE FUNCTIONAL DECLINE AND FRAILTY

PSYCHOSOCIAL AND PSYCOBIOLOGICAL APPROACH TO PREVENT AGE FUNCTIONAL DECLINE AND FRAILTY

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Activity details

This is a renewal of a previous commitment in the A3 Functional decline and frailty group. In the current commitment we focus specifically on the the relationship between stress and cognitive and physical functioning, and its effects on frailty. This commitment implies the development of a protocol for analyzing the effects of the interaction between aging and stress on cognitive function. Transversal and longitudinal designs are employed using different measures to assess acute responses to social stress in laboratory, including neuroendocrine (cortisol, alpha-amylase), cardiovascular (HRV, BP), affective and behavioral measures. These analyses are complemented with other such as Cortisol awakening response (CAR), which permit to obtain more basal information about the activity of the Hypothalamic-Pituitary-Adrenal axis activity. The impact of the personal characteristics and the coping style on the psychobiological impact of stress and cortisol on cognitive processes and ohysical functioning are also crucial to maintain the functioning associated with a satisfactory aging. Sex-related differences are considered and studied since differences between men and women can offer important onformation regarding frailty.
Action Group:
Lead organisation name: 
University of Valencia
Organisation country:
Contact person: 
Alicia Salvador
Contact person email: 
alicia.salvador@uv.es
Activity type:
Start date: 
01/10/2012
Geographic_coverage:
Last update: 09/01/2018

Current Status

Ongoing
Regarding the effects of acute stress on memory: We have finished the first studies investigating the effects of acute stress on working memory and long-term memory retrieval in healthy older people and the effects of some psychological factors on the stress response. These results have been published in several scientific articles. Currently, we are performing new experiments to investigate the effects of stress on other memory phases. Regarding the longitudinal studies investigating the relationship between HPA-axis activity and cognitive performance: We are new performing the second assessment of our participants (90 participants approx) and we are preparing reports of the first part of the longitudinal study. Also, different scientific articles have been published showing our cross-sectional results in healthy older people and in people with a duagnosis of hypertension.

Results

No results were indicated for this commitment.

Outcomes

No results were indicated for this commitment.