PROMISS (PRevention Of Malnutrition In Senior Subjects in the EU)

PROMISS (PRevention Of Malnutrition In Senior Subjects in the EU)

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Activity details

PROMISS’ mission is to conduct ground breaking research to contribute to the PRevention Of Malnutrition In Senior Subjects in the EU and to support active and healthy ageing (AHA). PROMISS’ work, led by the Vrije Universiteit Amsterdam (the Netherlands), relates to A3 Action Group preventing Frailty and Functional Decline by focusing on nutrition. PROMISS aims to unravel the relationships of daily intake, food characteristics, physical activity, and the oral and gut microbiota with appetite, malnutrition and clinical outcomes in community dwelling older adults. PROMISS has the ambition to increase the sustainability of older persons’ diets by searching for dietary strategies with minimal environmental impact. Therefore PROMISS implements a common vision on nutrition and frailty suitable to be scaled up at European level, cooperating with other EU projects and initiatives (e.g. JPI Malnutrition, NU-AGE, DEDIPAC), pooling synergies for a EU-led role in international settings. PROMISS will develop, promote and deploy innovative solutions and practical recommendations for AHA, coming forward with initiatives to be implemented in the coming 3 years, taking stock of the wide work done by European research, as well as build bridges with other EIP AHA Action groups for more integrated solutions to the challenges of ageing.
Action Group:
Lead organisation name: 
Vrije Universiteit, Amsterdam, the Netherlands
Organisation country:
Contact person: 
PROMISS Project Office
Contact person email:
Activity type:
Synergy led by:
Start date: 
End date: 
Last update: 31/01/2019

Current Status

Obtaining observational evidence by performing statistical analyses of existing data previously collected in five prospective cohort studies conducted among older adults (European as well as third countries Canada and USA) and four nutrition surveys conducted among older adults throughout Europe. These cohorts include the Longitudinal Aging Study Amsterdam (LASA, the Netherlands); the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES, Iceland); the Newcastle 85+ Study (UK); the Quebec Longitudinal Study on Nutrition and Aging (NuAge, Canada); and the Health, Aging and Body Composition Study (HABC, USA). At the moment analyses plan proposal for the cohort data and survey data are written and discussed by the researchers in order to determine the dietary characteristics and daily food intake patterns of older adults by appetite and malnutrition strata (low protein intake). Besides in work package 2 the focus is on daily physical activity and sedentary behavior patterns, the first aim is to determine daily physical activity, sedentary behavior and nap/sleep patterns of older adults. Analyses plans are written and the plan is to harmonize data across cohorts. Next to the observational analyses the preparations for a quantitative survey in five countries across Europe (UK, Finland, The Netherlands, Spain and Poland; n=± 350 per country) started. A mixed administration method will be considered, e.g. computer-assisted personal interviewing, computer-assisted web interviewing and Paper-and-Pencil Interviewing, etc. The questionnaire will take about 35 minutes to complete. The participants should be 70 years old and without cognitive impairment, as some questions require thinking or reflection upon their habits or preference. The main objective of the survey is to quantify specific attitudes and preferences of older adults, as food consumers, with regard to dietary and physical activity characteristics.


Title Planned Deadline Current Status Category Attachments
Website up and running ( 29/04/2016 Achieved Dissemination: Platforms/websites/social networks.
PROMISS leaflet 31/08/2016 Achieved Dissemination: Newsletters, blogs
The intestinal microbiota, energy balance, and malnutrition: emphasis on the role of short-chain fatty acids 23/03/2018 Achieved Research: Reports (reports, articles, findings) PDF icon wp3_fluitman_et_al._2017.pdf
Protein Intake and Mobility Limitation in Community-Dwelling Older Adults: the Health ABC Study 23/03/2018 Achieved Research: Reports (reports, articles, findings) PDF icon wp1_houston_et_al-2017-journal_of_the_american_geriatrics_society.pdf
Prevalence and determinants of low protein intake in very old adults: insights from the Newcastle 85+ Study 23/03/2018 Achieved Research: Reports (reports, articles, findings) PDF icon mendonca_et_al_2017_prevalence_and_determinants_of_low_protein_intake_in_the_very_old_ejon.pdf
Poor Appetite and Dietary Intake in Community-Dwelling Older Adults 23/03/2018 Achieved Research: Reports (reports, articles, findings) PDF icon wp1_meij_et_al-2017-journal_of_the_american_geriatrics_society.pdf
Low protein intake, muscle strength and physical performance in the very old: The Newcastle 85+ Study 23/03/2018 Achieved Research: Reports (reports, articles, findings) PDF icon granic_et_al_2017-low_protein_intake_and_phyiscal_performance_cn.pdf
Prospective associations of poor diet quality with long-term incidence of protein-energy malnutrition in community-dwelling older adults: the Health, Aging, and Body Composition (Health ABC) Study 23/03/2018 Achieved Research: Reports (reports, articles, findings) PDF icon hengeveld_et_al._2018_ajcn.pdf
Protein Intake and Disability Trajectories in Very Old Adults: The Newcastle 85+ Study 31/01/2019 Achieved Research: Reports (reports, articles, findings) PDF icon mendon-a_et_al-2018-journal_of_the_american_geriatrics_society.pdf
Potential of butyrate to influence food intake in mice and men 23/03/2018 Achieved Research: Reports (reports, articles, findings) PDF icon fluitman_2018_commentary_butyrate-appetite.pdf



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