VPHOP is a Collaborative Integrated Project which is developing a simulation-based technology to predict the risk of bone fracture in osteoporosis patients. Co-funded by the European Commission as part of the Seventh Framework Program, the project runs for 4 years starting from September 2008. The Project Consortium is coordinated by Rizzoli Orthopaedic Institute and gathers 19 European Organisations based in Italy, The Netherlands, Germany, Switzerland, Belgium, France, United Kingdom, Sweden, and Iceland. The project newsletter will keep you informed of its developments and achievements.