The INTEGRATE project aims to develop innovative infrastructures to enable data and knowledge sharing and to foster large-scale collaboration in biomedical research. INTEGRATE flexible infrastructure components and tools will bring together heterogeneous multi-scale biomedical data generated through standard and novel technologies within post-genomic clinical trials. It will also provide a seamless link to existing research and clinical infrastructures, such as clinical trials management systems, eCRFs, and hospital EHRs. Partially funded by the European Commission under the 7th Framework Programme, INTEGRATE is coordinated by a Consortium of six partners from different European countries. Each partner brings to the project its own expertise ranging from healthcare technology to clinical research coordination.