The Mediterranean Institute for Transplantation and High Specialisation Therapies (ISMETT) has recently launched a tele-health monitoring project for 30 Sicilian liver transplant patients during the post-transplant follow-up period. The new system will allow transplant patients to leave the hospital early and recover at home thanks to a telehealth monitoring system, which comes with an integrated camera, microphone and speakers for interactive video-conferences. Patients can now be monitored and supported from their homes, with the possibility of collecting biometric data, managing their treatment and offering face to face support via video conferencing.