Thanks to Information and Communication Technologies (ICT)it will be possible in the future to provide all citizens, regardless of their location, with better and personalised healthcare, achieving at the same time relevant cost savings for patients and the society at large. Citizens and business’ interactions with public authorities will be faster and more effective, also across the borders. A greater number of people will be able to live safely and independently, and those from disadvantaged groups will be able to get fully involved in society. Last but not least, ICT will help tackling environmental issues, such as energy saving, in the perspective of a sustainable growth. This booklet lists projects that illustrate these benefits and show the strong potential in addressing and solving societal challenges.