COMMODITY12 is a unique system for the analysis of multi-parametric medical data in patients suffering from diabetes. The consortium involves research institutes, university experts and industrial companies. Together they cover a broad field of expertise ranging from genomics, and medical knowledge to medical devices and e-health. COMMODITY12 will uptake the existing cutting-edge technologies and extend these technologies by combining state-of-the-art networks, software interoperation, and artificial intelligence techniques in order to realize the concept of translational medicine by means of a Personal Health System. Moreover, it will build a new level in patient empowerment, providing the tools for self-management support. Indirectly, this system will also help wider implementation of Personal Health Systems, reinforcing leadership and innovation capability of the European industry in that area.