University of Bath - United Kingdom
Alain Nogaret is a Professor of Physics at the University of Bath with research interests in quantum and nonlinear electronics. A growing research focus in his group is the understanding of physical processes that control the emergence of synchronization in local neural networks and the mechanisms of information coding. His group has developed nonlinear optimization tools that are used to infer the microscopic properties of ion channels from the analysis of macroscopic neuronal activity accessible to measurement. This approach provides a quantitative method for conditioning biocircuits, enabling them to build small silicon biocircuits and central pattern generators that respond identically to biological circuits when stimulated by arbitrary biological feedback. These devices are proving extremely useful to restore the rhythmic activity lost to disease and to provide therapies for chronic disease such as heart failure.