Open Innovation 2.0 (OI2) is a new paradigm which is about sustainable prosperity and value creation, and well-being. OI2 involves deep networking and collaboration amongst all actors in society to co-create value, to enhance and accelerate progress. Therefore, new methodologies, mechanisms, mind-sets, metrics like design thinking and prototyping are required. With the intention of bringing together thought leaders, senior decision makers, policy leaders, leading executives and social innovators, the European Commission, Open Innovation Strategy and Policy Group, Intel Labs Europe, Dublin City Council, Trinity College Dublin co-organise the Open Innovation 2.0 Conference on 20th and 21st May 2013 in Dublin. Speakers and participants of the Conference are expected to develop together a manifesto, platform and roadmap for sustainable economy and society development.