One year on from the adoption of the EU Directive on Patients’ Rights in Cross-Border Healthcare, this Symposium will look at the challenges to the implementation of cross-border healthcare and their effect on patient’s safety and quality, health professionals’ mobility and European standards for healthcare services. The Danish Presidency will explore the creation of an adequate information system for the general public regarding medical prescriptions with equal access to all Member States. Delegates will have the chance to exchange innovative evidence-based ideas alongside good practices linked to cooperation between border regions in Europe and national healthcare systems.