PETA International Science Consortium Ltd.
Company limited by guarantee
III - Non-governmental organisations
Non-governmental organisations, platforms and networks and similar
All Saints Street, 8
London N1 9RL
Ms Sandler Jessica
Ms Sandler Jessica
PETA International Science Consortium Ltd. ('PISC') represents the interests of its members and their individual supporters. PISC applies, co-ordinates and directs its own and its members' scientific and regulatory expertise to promote reliable and relevant strategies to reduce, and ultimately eliminate, the use of animals in experiments. PISC provides technical support to companies and researchers seeking to replace, reduce, or refine the use of animal tests, and advises its members with regard to providing financial support to companies to achieve this common goal.
In addition to assisting research organisations and private industries in the development of best practices, PISC interacts with national and international regulatory bodies and standards organisations to ensure that opportunities exist to increase and harmonise the use of validated non animal test methods. PISC engages with a number of regulatory bodies, including but not limited to the European Chemicals Agency (ECHA). This engagement involves participation in expert working groups, including as a member of the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) Stakeholder Forum (ESTAF), submission of comments on regulatory initiatives, direct communication and lobbying as appropriate.
An area of primary concern is the REACH (Registration, Evaluation, Authorisation and Restriction of Chemical Substances) regulation. This on-going extensive project includes working with ECHA and the European Commission regarding the use of animals as a last resort, and liaising with companies to ensure they implement validated alternatives to animal testing.
A significant objective is to influence international testing guidelines which determine the number of animals and the exact nature of the procedures to be used in globally standardised toxicity tests. We work extensively on these guidelines through the International Council on Protection of Animals in Organisation for Economic Cooperation and Development (OECD) Programmes (ICAPO), and we seek to ensure the best possible science and animal welfare (using reduction and refinement strategies) and the widest possible integration of alternatives to in vivo test methods in OECD guidelines and programmes. This work is critical to ensuring that the OECD's international test standards for human health and ecological safety use nonanimal methods and approaches. When working on behalf of ICAPO, PISC scientists represent animal protection organisations from North America, Europe, Japan and India.
PISC and its members regularly submit detailed scientific comments on a wide range of new test guidelines or those undergoing revision, thus influencing the development and validation of test guidelines from an early stage.
PISC ensures that information regarding the use of non animal tests is accessible to all audiences by publishing technical briefs and articles in peer-reviewed journals and by presenting at scientific, administrative and legislative conferences. These documents and presentations are available at www.piscltd.org.uk/scipubs.
In cases where promising in vitro techniques require additional development or validation in order to gain regulatory acceptance, PISC directs it members to assist in providing funding. Projects include the advancement of QSAR models to estimate chemical carcinogenicity and toxicity and other non animal models to test chemicals for acute toxicity, skin sensitisation and irritation, and endocrine activity.
• REGULATION (EC) No 1907/2006: Regulation concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)
• REGULATION (EC) No 440/2008: Regulation laying down test methods (TMR) pursuant to Regulation (EC) No 1907/2006
• REGULATION (EC) No 1272/2008: Regulation on classification, labelling and packaging (CLP) of substances and mixtures
• REGULATION (EU) No 528/2012: Regulation concerning the making available on the market and use of biocidal products
• REGULATION (EC) No 178/2002: Regulation laying down the general principles and requirements of food law
• REGULATION (EC) No 1223/2009 Regulation on cosmetic products
• DIRECTIVE 2010/63/EU: Directive on the protection of animals used for scientific purposes
• European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM)
• European Partnership for Alternatives Approaches to Animal Testing (EPAA)
• Organisation for Economic Co-operation and Development (OECD) Test Guidelines Programme
• OECD Cooperative Chemicals Assessment Programme
• OECD Quantitative Structure-Activity Relationships Project [(Q)SARs]
• OECD Adverse Outcome Pathway (AOP) development programme
• OECD programme on the safety of manufactured nanomaterials
PISC was registered as a company in November 2012, as set forth above. Previously PISC functioned as an unincorporated association. In the past year PISC has focused on the following EU initiatives:
1) Registration, Evaluation, and Authorisation of Chemical Substances (REACH) Regulation
PISC and its members have been actively addressing the animal testing implications of REACH since it was first announced, and in the past year continued to do so through:
• Extensive dialogue with ECHA and the European Commission (COM)
• Attendance at ECHA stakeholder days
• Attendance at Member States Committee meeting and Enforcement Forum
• Lobbying at the member state, ECHA and COM levels to ensure acceptance of the Extended One Generation Reproductive Toxicity Study
• Engaging with stakeholders, including industry bodies, companies and member state Directive 2010/63 and REACH competent authorities.
• Promoting the use of QSAR and read-across to meet REACH data requirements
• Working to reduce redundant and duplicative testing between the US Environmental Protection Agency (EPA) High Production Volume (HPV) chemical test rule and REACH
2) EURL ECVAM Stakeholder Forum (ESTAF)
PISC is a member of ESTAF which allows us to contribute to the validation process of in vitro methods through the assessment of submitted test methods and commenting on EURL ECVAM recommendations.
3) Harmonisation Efforts
Gains in one country or region are better served by assurances that those gains are meaningful elsewhere, including in the EU. PISC compiles and publishes a list of validated alternative methods, last updated in 2014 and coordinates efforts between countries in order to maximize harmonisation opportunities.
4) Organisation for Economic Cooperation and Development (OECD)
PISC provides extensive technical expertise to the OECD through the International Council on Animal Protection in OECD Programmes (ICAPO). This ensures that the OECD's proposed international test standards for both human health and ecological safety use nonanimal methods wherever possible and implement 3R approaches. PISC's OECD work in the past year includes:
• Participation in expert groups
• Submitting detailed scientific comments on test guidelines
• Attendance at the Working Group of the National Coordinators of the Test Guidelines Programme (WNT), which oversees the work of the OECD test guidelines programme.
5) Directive 2010/63/EU on the Protection of Animals Used for Scientific Purposes
In coordination with PISC, PETA Foundation UK worked to influence transposition of Directive 2010/63/EU into UK law which resulted in the majority of the UK’s higher standards being upheld. PISC continues to respond to government consultations, for example on the guidance documents prepared by the Home Office on the implementation of the Animals (Scientific Procedures) Act.
6) Military Trauma Training
PISC members PETA US, PETA Foundation UK and PETA Germany are working to replace the use of animals in military “live tissue” trauma training exercises with modern human simulation models and other non-animal training methods. PISC members have received confirmations of no animal use for military medical training from 21 European countries. PISC members has filed complaints with the UK, Denmark and Poland to end animal use in military trauma exercises
100%: 2 75%: 1 50%: 1 25%: 5
Jessica Sandler serves as director of PISC. She received her undergraduate degree from Harvard University and her graduate degree in environmental health sciences from The Johns Hopkins University. Jessica also serves as senior director of the PETA US Regulatory Testing Department.
Jabeen Akhtar has six years’ experience writing federal regulations at the US Environmental Protection Agency.
Dr. Julia Baines serves as science policy advisor for PISC. She has a PhD from the University of Liverpool with a background in animal behaviour and welfare.
Patricia Bishop has an undergraduate degree in wildlife ecology, a master’s degree in environmental science and 30 years of experience as a research scientist with the State of New York and advises PISC on endocrine-related testing issues and Tox21 methods.
Jeff Brown studied epidemiology and public health at George Washington University after receiving his undergraduate degree in cell and molecular biology and advises PISC on biologicals.
Dr. Alka Chandna advises PISC on ensuring that laboratory oversight bodies fulfil their legally mandated responsibilities, including minimising pain, discomfort and distress to animals through the implementation of best animal welfare practices.
Dr. Amy Clippinger has a PhD in cellular and molecular biology and genetics and conducted her post-doctoral research in the Cancer Biology Department at the University of Pennsylvania.
Dr. Ashley DeCoux has a PhD from the University of South Alabama, where she studied fibroblast biology in neonatal lung disease in the Department of Cell Biology and Neuroscience. She completed a post-doctoral fellowship at the University of Mississippi Medical Center in the Department of Physiology.
Dr. Christopher Fassbender has a PhD in biology and several years of research and teaching experience in ecotoxicology and zoology at the University of Heidelberg, Germany.
Shalin Gala serves PISC as a specialist in replacing the use of animals for medical and surgical training with simulation methods.
Justin Goodman advises PISC on research and campaigns to replace the use of animals in experiments, classroom education and medical training with nonanimal alternatives.
Erik R. Janus is President and Manager Member of M³ Technical & Regulatory Services, a consulting company working to support the future of chemical risk assessment through the advancement of modern nonanimal methods of toxicity and exposure evaluation.
Dr. Chaitanya Koduri advises PISC on science policy matters in India. He holds a bachelors degree in dental surgery and a master’s degree in nanotechnology.
Joe Manuppello has a master’s degree in molecular biology and genetics and 20 years of research experience at the University of Pennsylvania and advises PISC on chemical testing issues.
Karin Gabrielson Morton advises PISC on replacement alternatives and legislation and is a consultant at the Swedish Fund for Research Without Animal Experiments.
Dr. Monita Sharma received her PhD in biomedical sciences from Wright State University with nanotoxicology as the main area of focus. As the nanotoxicology specialist for PISC, Dr. Sharma researches and promotes human-relevant nonanimal methods to assess nanotoxicity.
Dr. Gilly Stoddart is the associate director of PISC and is also PETA Foundation UK’s Head of Science. She has a PhD in drug delivery from the Cardiff University and has seven years experience working in research and development.
Kristie Sullivan has a Masters of Public Health in toxicology from the University of Michigan and advises PISC on implementing policies that reduce the use of animals in industrial and government testing programs. She coordinates the efforts of the International Council for Animal Protection in OECD Programmes (ICAPO).
|No accredited persons|
People for the Ethical Treatment of Animals Foundation (PETA UK)
08/2013 - 07/2014
50,000 € - 99,999 €
No funding received from the EU institutions during the last closed financial year.
On 29 November 2012 PETA International Science Consortium Limited ("PISC Ltd") was incorporated under English law as a company limited by guarantee. All activities previously carried out by PISC were, on 29 November 2012 and thereafter, subsumed within PISC Ltd. In due course and as is required by English law, PISC Ltd will file annual company accounts at Companies House. PISC Ltd will operate on a 'not for profit' basis.
In order to provide meaningful figures representing the financial activity of PISC and PISC Ltd for the period 4/13 – 4/14, the financial data section (above) has been completed by applying reasoned proportions to the costs to the members of PISC (and PISC Ltd) of carrying out PISC related activities.
This is in accordance with guidance provided by the Joint Transparency Register Secretariat: Transparency Register Compliance Guidelines Ed No3 (Section A para 3) and the Frequently Asked Questions Version 2 (para 15).
By its registration the organisation has signed the Transparency Register Code of Conduct.