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Over the next few years, new legislation known as the CLP regulation is changing how chemical products are classified to identify hazards, and how this information is communicated on labels and safety data sheets (SDSs). This document is intended to provide practical guidance to employers and workers on how the directly acting CLP regulation (Regulation (EC) No 1272/2008 on the Classification, Labelling and Packaging of Substances and Mixtures) will affect the following worker protection directives: • chemical agents directive (98/24/EC); • carcinogens and mutagens directive (2004/37/EC); • safety signs directive (92/58/EEC); • pregnant workers directive (92/85/EEC); • young people at work directive (94/33/EC). These directives have been implemented in the national legislation of each Member State. Information on this legislation and general guidance on how to comply will normally be available from the authorities responsible for occupational health and safety in each Member State. This publication is available in printed format in English, French and German.