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index by sub-area 5.1.1. Sustainable agriculture/Animal Systems
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Defining and validating gut-health criteria in young pigs, based on digestive physiology, microbiology and mucosal immunology investigations for testing alternative strategies to in-feed antibiotics

Contract nr: QLK5-CT-1999-30522
Project type: RS (Research and Technological Development Project)
Starting date:
Duration: 42 months
Total cost: 5,532,475 EUR
EC Contribution: 3,853,157 EUR
Scientific Officer: Michel VAN DEN BOSSCHE
Research topic: 5.1.1. Sustainable agriculture/Animal Systems

Abstract:
Health degradation of pigs at weaning in intensive production systems is expected after the recent ban on in-feed antibiotics and metals by the EU. Many alternatives with claimed effectiveness have invaded the market prior to being fully evaluated. Our objective is to provide scientific basis for understanding the functional disturbances of the gut which favour enteric infections. We propose to use the disturbed weaned pig as a model for defining the major criteria for gut health. We will measure the changes occurring in gut physiology and digestion, mucosal integrity and function, bacterial populations, and intestinal immunity, using the most modern techniques. The ability of selected novel feed additives and rearing strategies to maintain or restore gut health will be assessed in large pig trials using the most pertinent defined health criteria. This will contribute to setting up a uniform approach to testing alternatives at EU level and will assist socio-economical partners in making well-informed decisions.


Coordinator
Bernard COQUET
Institut National de la Recherche Agronomique
Saint-Gilles
FRANCE
Tel.: +33 2 99285301
Fax: +33 2 99285300
E-mail: Bernard.Coquet@rennes.inra.fr


Partners
  Hans W. DE VRIES
Institute for Animal Science and Health (ID-Lelystad)
Lelystad
THE NETHERLANDS
Tel.: +31 320238010
Fax: +31 320238050
E-mail: postkamer@id.wag-ur.nl
  Baukje VRIESWIJK
Wageningen University
Wageningen
THE NETHERLANDS
Tel.: +31 317482260
Fax: +31 317484292
E-mail: baukje.vrieswijk@alg.kb.wau.nl
  Michael SPECKESSER
Medical School of Hannover
Hannover
GERMANY
Tel.: +49 511 5326034
Fax: +49 511 5326032
E-mail: speckesser.michael@mh-hannover.de
  Giuseppe ROTILIO
Istituto Nazionale della Nutrizione
Roma
ITALY
Tel.: +39 065032420
Fax: +39 0651957031
E-mail: president@inn.ingrm.it
  Piet VAN DER AAR
Stichting Instituut voor de veevoeding "De Schothorst."
Lelystad
THE NETHERLANDS
Tel.: +31 320252294
Fax: +31 320255030
E-mail: info@schothorst.nl
  Klaus ENDER
Forschungsinstitut für die Biologie landwirtschaftlicher Nutztiere
Dummerstorf
GERMANY
Tel.: +49 3820 868600
Fax: +49 3820 868602
E-mail: ender@fbn-dummerstorf.de
  Rachael FLEETWOOD
The University of Bristol
Langford, Bristol.
UNITED KINGDOM
Tel.: +44 1179 287910
Fax: +44 1179 250900
E-mail: rachael.parsons@bristol.ac.uk
  Daniel BARBACE
Institut National de la Recherche Agronomique
Toulouse
FRANCE
Tel.: +33 5 61285220
Fax: +33 5 61285280
E-mail: daniel.barbace@toulouse.inra.fr
  Gilberto GOVI
Università di Bologna
Reggio Emilia
ITALY
Tel.: +39 051267592
Fax: +39 051234313